Abnormal scattergrams and cell population data generated by fully automated hematological analyzers: New tools for screening malaria infection?

International Journal of Laboratory Hematology
S BuoroG Lippi

Abstract

Malaria is a life-threatening infectious disease, which has been for long confined to specific endemic areas. Nevertheless, the recent increase in immigration flows from endemic regions and imported cases has reemphasized many diagnostic challenges in Western countries, thus paving the way to introduce rapid and accurate strategies for screening subjects with suspected Malaria infection. Therefore, the aim of this article was to describe our recent experience with Sysmex XN-module for rapid screening of subjects with suspected Malaria. Fourteen patients admitted to the Emergency Department (Papa Giovanni XXIII Hospital Bergamo, Italy) with a clinical suspicion of Malaria infection were evaluated, along with 1047 control samples. The analysis of peripheral blood was performed with XN-module, and results were then compared to optical microscopy. Nine patients were positive to Plasmodim falciparum, 3 to Plasmodim vivax, one to Plasmodim ovale, and one to Plasmodim malarie. Characteristic abnormalities could be observed in both white blood cell differential (WDF) and white cell nucleated (WNR) scattergrams (sensitivity 0.64 and specificity 1.0) in 9 samples with parasites at gametocyte or schizos stage irrespective of Plasmodium sp...Continue Reading

References

Dec 3, 1999·Clinical and Laboratory Haematology·T Hänscheid
Dec 3, 1999·Clinical and Laboratory Haematology·J J Hoffmann, J M Pennings
Feb 15, 2002·Clinical and Laboratory Haematology·C S ScottT L Coetzer
Jul 19, 2005·Laboratory Hematology : Official Publication of the International Society for Laboratory Hematology·P W BarnesUNKNOWN international consensus group for hematology
Mar 9, 2010·The American Journal of Tropical Medicine and Hygiene·Germán Campuzano-ZuluagaGermán Campuzano-Maya
Dec 2, 2010·Malaria Journal·Germán Campuzano-ZuluagaMartin P Grobusch
Aug 2, 2012·Journal of Clinical Pathology·Carol BriggsSamuel J Machin
Sep 17, 2013·International Journal of Laboratory Hematology·P DubreuilM Zandecki
Jul 19, 2016·International Journal of Laboratory Hematology·T B KengUNKNOWN International Council for Standardization in Haematology (ICSH)
May 10, 2017·The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Médicale·Samina Naz MukryTahir Sultan Shamsi
Sep 20, 2017·Diagnostics·Francis D KrampaProsper Kanyong
Oct 5, 2017·International Journal of Laboratory Hematology·S PipitoneS Buoro

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Citations

Feb 9, 2020·Journal of Clinical Pathology·Cécile DumasAnne-Lise Bienvenu
Sep 12, 2019·International Journal of Laboratory Hematology
Oct 21, 2020·International Journal of Laboratory Hematology·Ivana LapićVatroslav Šerić
Aug 11, 2021·International Journal of Laboratory Hematology·Hee Jin HuhSeok-Lae Chae

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