PMID: 2125404Dec 1, 1990Paper

Abnormal small bowel permeability and duodenitis in recurrent abdominal pain

Archives of Disease in Childhood
S B van der MeerJ W Arends

Abstract

Thirty nine children with recurrent abdominal pain aged between 5.5 and 12 years, underwent endoscopic duodenal biopsy to find out if there were any duodenal inflammatory changes, and if there was a relationship between duodenal inflammation and intestinal permeability to 51Cr-EDTA. Duodenal inflammation was graded by the duodenitis scale of Whitehead et al (grade 0, 1, 2, and 3). In 13 out of 39 patients (33%) definite signs of inflammation were found (grade 2 and 3). Intestinal permeability to 51Cr-EDTA in patients with duodenitis (grade 1, 2, and 3) was significantly higher (4.42 (1.73)%) than in patients with normal (grade 0) duodenal biopsy appearances (3.3 (0.9)%). A significant association was found between duodenal inflammation and abnormal intestinal permeability. Our results give further evidence that there is an intestinal origin of these patients' complaints.

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Citations

Aug 1, 1992·European Journal of Pediatrics·I MavromichalisG Slavin
Dec 31, 1997·Italian Journal of Neurological Sciences·G LanziC Termine
Mar 4, 2000·Journal of Pediatric Gastroenterology and Nutrition·E OlafsdottirG Fluge
Jan 1, 1996·Journal of Child Psychology and Psychiatry, and Allied Disciplines·M E Garralda
Feb 1, 1992·Acta Paediatrica·S B van der MeerJ W Arends
Jul 1, 1994·Acta Paediatrica·T Lindberg
Oct 1, 1993·Archives of Disease in Childhood·M S Murphy
Jan 1, 1990·Pediatric Radiology·S B van der MeerJ M van Engelshoven
Nov 1, 1992·European Journal of Pediatrics·S B van der MeerJ W Arends
May 1, 1995·European Journal of Pediatrics·I MavromichalisM M Giala
Dec 1, 1996·European Journal of Pediatrics·T VukavićD Pavkov
Jun 6, 2015·Journal of Paediatrics and Child Health·Mario BarretoMaria Pia Villa
Jun 1, 1993·Clinical Pediatrics·R Wyllie, M Kay
Jan 16, 2007·The American Journal of Gastroenterology·Kalpesh ThakkarHashem B El Serag
Jul 1, 1991·Archives of Disease in Childhood·I MavromichalisG Slavin

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