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Abnormal vasculature interferes with optic fissure closure in lmo2 mutant zebrafish embryos

Developmental Biology

Sep 15, 2012

Omri WeissAdi Inbal

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Abstract

Ocular coloboma is a potentially blinding congenital eye malformation caused by failure of optic fissure closure during early embryogenesis. The optic fissure is a ventral groove that forms during optic cup morphogenesis, and through which hyaloid artery and vein enter and leave the dev...read more

Mentioned in this Paper

Blood Supply Aspects
In Situ Nick-End Labeling
Fertilization
Angiogenic Process
VP-16
Cell Death
Mutant
Oligonucleotide Primers
Benign Neoplasm of Retina
GATA1 gene
2
34
Paper Details
References
  • References31
  • Citations13
12

Abnormal vasculature interferes with optic fissure closure in lmo2 mutant zebrafish embryos

Developmental Biology

Sep 15, 2012

Omri WeissAdi Inbal

PMID: 22819672

DOI: 10.1016/j.ydbio.2012.06.029

Abstract

Ocular coloboma is a potentially blinding congenital eye malformation caused by failure of optic fissure closure during early embryogenesis. The optic fissure is a ventral groove that forms during optic cup morphogenesis, and through which hyaloid artery and vein enter and leave the dev...read more

Mentioned in this Paper

Blood Supply Aspects
In Situ Nick-End Labeling
Fertilization
Angiogenic Process
VP-16
2
34

Related Papers

Paper Details
References
  • References31
  • Citations13
12

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