PMID: 11606856Oct 19, 2001Paper

Abnormal vitamin levels in patients receiving home total parenteral nutrition

Journal of Clinical Gastroenterology
V MikalunasR M Craig

Abstract

The administration of multivitamins to patients receiving home parenteral nutrition (HPN) was decreased from once daily to three times weekly during the parenteral multivitamin shortage in 1997. Blood vitamin levels were measured to examine whether the decrement in the infused vitamins affected the levels. Six patients with normal renal and liver function, receiving HPN for 6 months to 10 years, were studied 6 months after the institution of 10 mL of multivitamins thrice weekly. Two patients with renal insufficiency who required hemodialysis and HPN were also studied. Multivitamin administration was eliminated in one patient and was reduced to once weekly when elevated pyridoxine levels were found in association with possible neurotoxicity. Five of the six patients with normal renal function had low serum ascorbic acid levels. Serum riboflavin levels were found to be low in one patient, serum pyridoxine was low in one, serum retinoids were low in three, and serum niacin was low in one. There were no clinically obvious untoward effects caused by the vitamin deficiencies. Each of the dialysis patients had elevated serum pyridoxine levels and had some neurologic disturbance (peripheral neuropathy, involuntary movements). The serum...Continue Reading

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Citations

Dec 1, 2002·Nutrition Research Reviews·Angel Gil, Ricardo Rueda
Mar 6, 2016·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Loris PironiUNKNOWN Home Artificial Nutrition & Chronic Intestinal Failure Special Interest Group of ESPEN
Jul 27, 2011·The Surgical Clinics of North America·Kristen M RhodaEzra Steiger
Jun 2, 2011·JPEN. Journal of Parenteral and Enteral Nutrition·Camila Bitu Moreno BragaSelma Freire de Carvalho da Cunha
Dec 6, 2008·The American Journal of Clinical Nutrition·Laura E MatareseKareem M Abu-Elmagd
Jan 12, 2019·Current Opinion in Gastroenterology·Martyn Dibb, Simon Lal
Dec 31, 2020·Therapeutics and Clinical Risk Management·Carlos-Alberto Calderon-OspinaAna María Paez-Hurtado

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