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Abnormal X Chromosome Inactivation in Females with Major Psychiatric Disorders

bioRxiv

Sep 23, 2014

Bao-Hu JiXianjin Zhou

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Abstract

Bipolar disorder, major depression and schizophrenia are severe brain disorders. No biological hallmark has been identified for any of these disorders. Here, we report that abnormal X chromosome inactivation (XCI) often presents in lymphoblastoid cells of female patients with different ...read more

Mentioned in this Paper

Mental Retardation
KDM5C gene
Lysine
Psychiatry Specialty
X Chromosome
Study
Klinefelter's Syndrome - Male With More Than Two X Chromosomes
Schizophrenia
General Population
Mutation Abnormality
5
11
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  • Abnormal X Chromosome Inactivation in Females with Major Psychiatric Disorders

    bioRxiv

    Sep 23, 2014

    Bao-Hu JiXianjin Zhou

    PMID: 990009555

    DOI: 10.1101/009555

    Abstract

    Bipolar disorder, major depression and schizophrenia are severe brain disorders. No biological hallmark has been identified for any of these disorders. Here, we report that abnormal X chromosome inactivation (XCI) often presents in lymphoblastoid cells of female patients with different ...read more

    Mentioned in this Paper

    Mental Retardation
    KDM5C gene
    Lysine
    Psychiatry Specialty
    X Chromosome
    5
    11

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