ABO blood group-incompatible living donor kidney transplantation: a prospective, single-centre analysis including serial protocol biopsies

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Tobias OettlMichael Dickenmann

Abstract

ABO incompatible kidney transplantation using antigen-specific immunoadsorption is increasingly performed but data on outcome, complications and protocol biopsies are still scarce. The present prospective single-centre study was aimed at these issues. This was a prospective single-centre cohort study of 10 successive ABO incompatible living donor kidney transplantations at the University Hospital Basel from September 2005 to October 2007. The following parameters were closely monitored during the whole follow-up: graft function, albuminuria, blood group antibody titres, CD19+ cell count, total IgG and IgG subclasses, CMV antigenaemia, decoy cells in the urine, EBV and polyoma BK virus PCR in the blood. Protocol biopsies were performed on Days 0 and 7 after 3, 6, 12 and 18 months. Patient and graft survival is 100% after a median follow-up of 489 days (range 183-916 days). Median serum creatinine is 137 micromol/l (range 70-215 micromol/l), and median urine albumin-creatinine ratio (UACR) is 3.1 mg/ mmol (range 0.6-7.8 mg/mmol) at the time of the last follow-up. All patients had sustained diminished CD19+ cell count and/or total IgG concentrations. Neither CMV antigenaemia nor EBV replication in the blood was observed. Seven pat...Continue Reading

References

May 16, 2002·Cerebrovascular Diseases·Masahiko HirokiMasaya Oda
Aug 16, 2002·The New England Journal of Medicine·Hans H HirschJürg Steiger
Jun 5, 2003·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Lorraine C RacusenKiril Trpkov
Jun 16, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Kota TakahashiUNKNOWN Japanese ABO-Incompatible Kidney Transplantation Committee
Sep 17, 2004·Transplantation·Mark D StegallJames M Gloor
Jan 8, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Gunnar TydénIngela Fehrman
Apr 21, 2006·Xenotransplantation·Gunnar TydénIngela Fehrman
Aug 8, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M HaasR A Montgomery
Aug 24, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·H GenbergG Tydén
Mar 14, 2007·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·K SolezJ J Weening
Jan 25, 2008·Transplantation·Robert A Montgomery, Jayme E Locke
Jan 1, 2008·Transplantation·Behrooz Broumand, Mehdi Rambod

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Citations

May 31, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Antje HabichtAnke Schwarz
Jul 9, 2010·Current Opinion in Organ Transplantation·Raymond J Lynch, Jeffrey L Platt
May 26, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Adnan SharifEdward Kraus
Sep 10, 2014·Transplant Immunology·K BuddingH G Otten
Oct 2, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Verena BröckerJan U Becker
Sep 18, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·UNKNOWN European Renal Best Practice Transplantation Guideline Development Group
Mar 29, 2014·Journal of Transplantation·Madelon van AgterenMichiel G H Betjes
Dec 5, 2014·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Adam RemportMiklos Z Molnar
Sep 2, 2015·Nature Reviews. Nephrology·Georg A BöhmigThomas Wekerle
Dec 17, 2011·Journal of Transplantation·Milljae Shin, Sung-Joo Kim
Apr 14, 2017·Transplant International : Official Journal of the European Society for Organ Transplantation·Bonnie E LonzeRobert A Montgomery
Jul 14, 2012·Current Opinion in Organ Transplantation·Thomas Fehr, Georg Stussi
Jul 25, 2015·Annals of Laboratory Medicine·Do Kyun KimHyung Jik Kim
Nov 13, 2009·Current Opinion in Organ Transplantation·Mark Haas
Apr 28, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A A R TobianK E King
Dec 1, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S SchaubM Mayr
Jul 12, 2016·Transfusion·Beatrice DrexlerMichael Dickenmann
Jan 25, 2012·Journal of Clinical Apheresis·Sven TeschnerVolker Burst
Nov 13, 2014·Transplant International : Official Journal of the European Society for Organ Transplantation·Stefan ZschiedrichTobias B Huber
Jan 30, 2014·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M HaasUNKNOWN Banff meeting report writing committee
Jan 16, 2009·Transplant International : Official Journal of the European Society for Organ Transplantation·Daisuke TokiKazunari Tanabe
May 5, 2011·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Christopher O C Bellamy
Feb 19, 2013·Transplant International : Official Journal of the European Society for Organ Transplantation·A Nicholas R BarnettNizam Mamode
Mar 6, 2015·Journal of Clinical Apheresis·Julie M Yabu, Magali J Fontaine
Jun 23, 2015·Transplant International : Official Journal of the European Society for Organ Transplantation·Lionel CouziNizam Mamode
Sep 4, 2015·Clinical Transplantation·Martina KochBjoern Nashan
Mar 7, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·P Hirt-MinkowskiS Schaub
Nov 6, 2013·Transplant International : Official Journal of the European Society for Organ Transplantation·A Nicholas R BarnettNizam Mamode
Jul 30, 2015·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Annelies E de WeerdMichiel G H Betjes
May 6, 2016·Clinical Transplantation·Anna Sánchez-EscuredoFritz Diekmann
Jun 30, 2009·Wiener klinische Wochenschrift·Michael HaidingerGeorg A Böhmig
Mar 3, 2012·Transplantation·Christian MorathVedat Schwenger
Aug 23, 2021·Transplantation Proceedings·Joelle HandschinPatricia Hirt-Minkowski
Jul 28, 2010·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Greg A KnollG V Ramesh Prasad
Dec 13, 2019·Case Reports in Nephrology and Dialysis·Davide SpicaPatricia Hirt-Minkowski

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