ABO blood group is a risk factor for coronary artery disease in patients with poor blood pressure control

Clinical and Experimental Hypertension : CHE
Bing-Yang ZhouJian-Jun Li

Abstract

Few studies had examined the role of ABO blood groups on CAD in hypertensive patients with different blood pressure (BP) controls. A total of 2708 patients with primary hypertension (HTN) were consecutively enrolled and underwent coronary angiography (CAG) due to angina-like chest pain. The severity of coronary artery stenosis was assessed by Gensini score (GS). Patients were divided into two groups due to results of CAG: HTN with CAD (n = 2185) and HTN without CAD (n = 523). Poor BP control was defined as systolic BP (SBP) ≥ mean in the study. Multivariable regression analysis was used to determine the potential impact of ABO blood groups on risk of the presence and severity of CAD. Compared to HTN without CAD group, the percentage of A blood group was statistically higher and O blood group was significantly lower in HTN with CAD group. Moreover, percentage of the angiography-proven CAD was higher in A blood group than that in non-A blood group (p < 0.05). After adjusting for confounding factors, A blood group was independently associated with CAD (odds ratio (OR): 1.422; 95% confidence interval (CI): 1.017-1.987; p = 0.039) and GS (β = 0.055, p = 0.046) in patients with poor BP control. A blood group was an independent risk f...Continue Reading

References

Jan 1, 1997·American Journal of Hypertension·W B StrawnC M Ferrario
Aug 10, 2005·International Journal of Cardiology·Alireza AmirzadeganHamidreza Goodarzynejad
Apr 8, 2010·Atherosclerosis·Clara CarpeggianiAntonio L'abbate
Jan 20, 2012·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Patricia GassóAmalia Lafuente
Jun 28, 2012·BJOG : an International Journal of Obstetrics and Gynaecology·B K LeeM Reilly
Jun 29, 2012·Seminars in Thrombosis and Hemostasis·Francesco DentaliMassimo Franchini
Aug 17, 2012·Arteriosclerosis, Thrombosis, and Vascular Biology·Meian HeLu Qi
Jun 18, 2014·Journal of Thrombosis and Thrombolysis·Ian J WelsbyMark Stafford-Smith
Feb 7, 2016·The Journal of Surgical Research·Ye-Qiong XuLi-Qing Qiu
Mar 31, 2016·Diabetes & Metabolic Syndrome·Masanori ShimodairaTomohiro Nakayama

❮ Previous
Next ❯

Citations

Feb 14, 2020·BMJ Open·Nur Hidayah DahalanSiti Mardhiana Binti Mohamad
Jul 7, 2020·Journal of Cardiovascular and Thoracic Research·Ahmad SeparhamNader D Nader

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.