Abomasal amino acid infusion in postpartum dairy cows: Effect on whole-body, splanchnic, and mammary glucose metabolism

Journal of Dairy Science
C E GalindoH Lapierre

Abstract

Nine Holstein cows fitted with rumen cannulas and indwelling catheters in splanchnic blood vessels were used to study the effects of supplementing AA on milk lactose secretion, whole-body rate of appearance (WB-Ra) of glucose, and tissue metabolism of glucose, lactate, glycerol, and β-OH-butyrate (BHBA) in postpartum dairy cows according to a generalized randomized incomplete block design with repeated measures in time. At calving, cows were blocked according to parity (second and third or greater) and were allocated to 2 treatments: abomasal infusion of water (n=4) or abomasal infusion of free AA with casein profile (AA-CN; n=5) in addition to the same basal diet. The AA-CN infusion started with half the maximal dose at 1 d in milk (DIM) and then steadily decreased from 791 to 226 g/d from DIM 2 to 29 to cover the estimated essential AA deficit. On DIM 5, 15, and 29, D[6,6-(2)H2]-glucose (23.7 mmol/h) was infused into a jugular vein for 5h, and 6 blood samples were taken from arterial, portal, hepatic, and mammary sources at 45-min intervals, starting 1h after the initiation of the D[6,6-(2)H2]glucose infusion. Trans-organ fluxes were calculated as veno-arterial differences times plasma flow (splanchnic: downstream dilution of...Continue Reading

References

Jan 1, 1977·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·J W Phillips, F J Hird
Jan 1, 1977·Journal of Dairy Science·J W Young
Aug 1, 1976·Archives of Biochemistry and Biophysics·H G Windmueller, A E Spaeth
Mar 1, 1992·The Journal of Nutrition·R S EmeryT H Herdt
Sep 1, 1970·The American Journal of Physiology·E N BergmanC F Kaufman
May 1, 1995·The British Journal of Nutrition·G E LobleyD A Farningham
Oct 26, 2001·Gastroenterology·S R van der SchoorP J Reeds
May 2, 2003·Journal of Animal Science·C J RichardsG B Huntington
Jun 17, 1960·Biochimica Et Biophysica Acta·G I PRITCHARD, S B TOVE
Aug 19, 2007·Journal of Dairy Science·L DoepelH Lapierre
Aug 13, 1948·Science·E Haas, H Goldblatt
Nov 13, 2009·Journal of Animal Physiology and Animal Nutrition·H A Van Dorland, R M Bruckmaier
Nov 26, 2009·American Journal of Physiology. Endocrinology and Metabolism·Dan ZhengRichard N Bergman
Dec 21, 2010·IUBMB Life·Jörg R AschenbachGregory B Penner
Apr 29, 2011·Journal of Dairy Science·B M L Raun, N B Kristensen
Mar 1, 2009·Animal : an International Journal of Animal Bioscience·H LapierreG E Lobley
Jul 1, 2010·Animal : an International Journal of Animal Bioscience·J J Loor
May 11, 2012·Journal of Animal Science·H LapierreS Lemosquet
Dec 6, 2012·American Journal of Physiology. Endocrinology and Metabolism·Monika M GadhiaPaul J Rozance
Jul 5, 2013·Animal : an International Journal of Animal Bioscience·M Larsen, N B Kristensen

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Citations

Nov 6, 2018·Journal of Dairy Science·T Amirabadi FarahaniM Kazemi-Bonchenari
Jun 12, 2018·Current Drug Metabolism·Feiran WangShengli Li
Sep 25, 2019·Animals : an Open Access Journal From MDPI·Eduardo Marostegan PaulaAntonio Pinheiro Faciola
Mar 10, 2021·Journal of Dairy Science·Fabiana F CardosoMarina A C Danes

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