DOI: https://doi.org/10.51161/rems/972Apr 23, 2021Proceedings Paper

ABORDAGENS TERAPÊUTICAS IMUNOLÓGICAS NO MANEJO DA EPIDERMÓLISE BOLHOSA: UMA REVISÃO DE LITERATURA

Felipe Marti Garcia Chavez, Victória Nunes Amaru

Abstract

Introdução: A epidermólise bolhosa (EB) é uma doença congênita, rara, autossômica dominante, autoimune da pele que pode ter acometimento multissistêmico e levar a malignidade. Ocorre devido a mutações nas proteínas de ancoragem entre a epiderme e a derme, e se caracteriza pela formação de vesículas ou bolhas principalmente em locais de maior atrito. Essa patologia é subdivida em quatro tipos de acordo com a sua proteína mutante: simples, juncional, distrófica e síndrome de Kindler. Além disso, a EB apresenta elevada morbimortalidade pois não há tratamento específico. Objetivos: Realizar um levantamento bibliográfico para descrever e comparar as principais atualizações terapêuticas de caráter imunológico que auxiliam no tratamento da epidermólise bolhosa a fim de conscientizar os profissionais da saúde acerca do tema. Material e métodos: Trata-se de um estudo de revisão de literatura de cunho descritivo e analítico. Foi realizada uma busca eletrônica nas bases de dados Pubmed, Biblioteca Virtual em Saúde, Schoolar Google e Scielo publicados entre 2013 e 2021. As palavras de busca foram: epidermólise bolhosa, tratamento imunológico, epidermolysis bullosa, immunological treatment. Foram selecionados 14 estudos contendo dados sobre...Continue Reading

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