PMID: 9663446Jul 15, 1998Paper

About 8-hour variation of circulating human endothelin-1

Peptides
M HeroldF HALBERG

Abstract

Plasma endothelin-1 (ET-1) and cortisol were measured around the clock at hourly intervals on 7 clinically healthy, diurnally active, nocturnally resting subjects 22-27 years of age. The circadian rhythm in cortisol is demonstrated for each subject (p < or = 0.020) as well as on a group basis (p = 0.002), peaking in the morning. By contrast, the circadian variation of ET-1 is statistically significant in only one of the subjects, and it is not detected for the group as a whole (p > 0.20). Instead, ET-1 is characterized by an about 8-h component (p < 0.001) that is not found for cortisol.

References

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Citations

Oct 24, 2003·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·K OtsukaF Halberg
Jan 20, 2004·Journal of Circadian Rhythms·Franz HalbergJarmila Siggelova
Jan 18, 2014·Psychosomatic Medicine·Luba YammineJanet C Meininger
Feb 19, 2008·Translational Research : the Journal of Laboratory and Clinical Medicine·Anne CharlouxBernard Geny
Dec 3, 2003·Journal of Experimental Therapeutics & Oncology·Franz Halberg Governor Shri Vishnu Kant Shastri
Jan 5, 2002·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·K OtsukaF Halberg
Apr 20, 2004·Regulatory Peptides·Anne CharlouxGabrielle Brandenberger
Mar 10, 2005·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Franz HalbergGermaine Cornélissen
Jun 2, 2000·Perceptual and Motor Skills·G Cornélissen, F Halberg
Dec 12, 2019·Pharmaceutical Research·Anke-Katrin VolzThorsten Lehr
Feb 1, 2020·Acta Histochemica Et Cytochemica·Ryutaro OnoKazuhiro Yagita
Dec 17, 2020·Physiology·Lauren G DoumaMichelle L Gumz

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