PMID: 8951210Nov 1, 1996Paper

Abscess within a brain metastasis

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
W P Ng, A Lozano

Abstract

Neoplastic metastases to the cerebellum are a frequent complication in patients with carcinoma. However, the co-existence of an abscess within a CNS metastasis is a rare event. We report the case of a 79-year-old woman with two cerebellar abscesses within metastatic lesions in the cerebellum. She presented with a rapidly progressing syndrome characterized by elevated intracranial pressure and cerebellar findings. At surgery, a purulent exudate within discrete metastatic tumours was identified. Pathological and microbiological examinations confirmed the coexistence of an abscess within a metastatic carcinoma. The radiological diagnosis o f intracranial abscesses and metastases can be non-specific and brain imaging may not reliably identify both processes when they coexist. Furthermore, brain metastases often contain liquefied material which can be mistaken for tissue necrosis rather than an infectious process. It is important to be aware that a brain metastasis can also be infected. Therefore, acquisition of lesional tissue for both pathological and microbiological examinations is essential for accurate diagnosis and to direct optimal therapy in situations where the intracranial lesion could be either an abscess or a metastatic ...Continue Reading

References

Jan 1, 1979·Archives of Neurology·E B Rotheram, L A Kessler
Jun 1, 1978·Neurology·H D Weiss, E P Richardson
Nov 1, 1978·Journal of Neurosurgery·M L RosenblumL Pitts
Feb 22, 1990·The New England Journal of Medicine·R A PatchellB Young
Apr 1, 1988·Neurosurgery·S Stephanov

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Citations

May 30, 2008·The Kaohsiung Journal of Medical Sciences·Tai-Hsin TsaiAnn-Shung Lieu
Feb 4, 2010·Journal of Neurosurgery·Aliasgar Moiyadi, Prakash Shetty
Dec 13, 2006·Neurosurgery·Christopher R P LindArnold P L Bok

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