Absence of back to school peaks in human rhinovirus detections and respiratory symptoms in a cohort of children with asthma

Journal of Medical Virology
Sacha Stelzer-BraidWilliam D Rawlinson

Abstract

Much of what is known about the seasonality of human rhinovirus (hRV) infections has been learned from the study of acute asthma exacerbations presenting to emergency care, including those among children at the start of the school term. Much less is known about the patterns of hRVs in the community. In this study, viruses and day-to-day symptoms of asthma and colds were monitored twice weekly in 67 children with asthma aged 5-12 years, over a 15 month period in Sydney, Australia. Overall hRV was detected in 314/1232 (25.5%) of nasal wash samples and 142/1231 (11.5%) of exhaled breath samples; of these, 231 and 24 respectively were genotyped. HRVs were detected with similar prevalence rate throughout the year, including no peak in hRV prevalence following return to school. No peaks were seen in asthma and cold symptoms using twice-weekly diary records. However, over the same period in the community, there were peaks in asthma emergency visits both at a large local hospital and in state-wide hospitalizations, following both return to school (February) and in late autumn (May) in children of the same age. This study suggests that hRV infections are common throughout the year among children, and differences in virus prevalence alon...Continue Reading

References

Mar 20, 2001·American Journal of Respiratory and Critical Care Medicine·C AlmqvistP Malmberg
Jan 8, 2005·The Journal of Allergy and Clinical Immunology·Neil W JohnstonMalcolm R Sears
Aug 15, 2006·Public Health·D LincolnJ Beard
Feb 13, 2007·Archives of Environmental & Occupational Health·Wansoo Im, Dona Schneider
Jul 31, 2007·The Journal of Allergy and Clinical Immunology·Malcolm R Sears, Neil W Johnston
Dec 7, 2007·Journal of Clinical Microbiology·Xiaoyan LuDean D Erdman
Jan 4, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kerrianne N HuynhEuan R Tovey
Feb 6, 2008·The Journal of Infectious Diseases·Ville PeltolaTimo Hyypiä
Mar 20, 2008·PloS One·Heather PowellPeter G Gibson
Nov 26, 2008·The Journal of Allergy and Clinical Immunology·E Kathryn MillerUNKNOWN New Vaccine Surveillance Network
Apr 10, 2009·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Kristen B Van DoleLinda Nelsen
Jul 25, 2009·Journal of Medical Virology·Sacha Stelzer-BraidEuan R Tovey
Aug 12, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jean-Baptist du PrelHeinz-Josef Schmitt
Sep 4, 2009·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Oded ScheuermanBen-Zion Garty
Feb 4, 2010·Reviews in Medical Virology·Katherine E Arden, Ian M Mackay
Apr 16, 2010·The Journal of Allergy and Clinical Immunology·Jaime P OlenecJames E Gern
Jul 9, 2010·The Journal of General Virology·Peter SimmondsTapani Hovi
Sep 8, 2010·Lancet·William W BusseJames E Gern
Sep 28, 2010·Medical Hypotheses·E R Tovey, W D Rawlinson
Oct 11, 2011·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Marieke M van der ZalmCornelis K van der Ent
Mar 21, 2012·Journal of Medical Virology·Clayton O OnyangoD J Nokes
Mar 24, 2012·Current Opinion in Virology·Natalie Pica, Nicole M Bouvier
Aug 28, 2012·American Journal of Respiratory and Critical Care Medicine·Wai-Ming LeeJames E Gern
Nov 14, 2012·The Journal of Allergy and Clinical Immunology·Jodell E LinderE Kathryn Miller
May 30, 2013·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·E Kathryn Miller, Ian M Mackay
Dec 6, 2014·The Journal of Allergy and Clinical Immunology·Euan R ToveyGuy B Marks

❮ Previous
Next ❯

Citations

Apr 25, 2019·Journal of Medical Virology·Gregory J WalkerWilliam D Rawlinson
Nov 30, 2019·Current Allergy and Asthma Reports·Evin HowardWanda Phipatanakul
Jul 28, 2020·The Lancet. Respiratory Medicine·Kevin P Fennelly
Nov 6, 2018·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Toby C LewisUNKNOWN Community Action Against Asthma SteeringCommittee

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Acute viral rhinopharyngitis

Acute viral rhinopharyngitis, also known as "common cold", is an acute, self-limiting viral infection of the upper respiratory tract involving the nose, sinuses, pharynx and larynx. Discover the latest research on acute viral rhinopharyngitis here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Related Papers

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Kevin B WeissEvalyn N Grant
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
J E Gern
The Journal of Allergy and Clinical Immunology
Kristiina MalmströmMika J Mäkelä
© 2021 Meta ULC. All rights reserved