PMID: 2500336Jan 1, 1989Paper

Absence of mutagenic interaction between microwaves and mitomycin C in mammalian cells

Environmental and Molecular Mutagenesis
M L MeltzD N Erwin

Abstract

Evidence in the literature from in vitro and in vivo studies as to whether or not radiofrequency radiation (RFR) in the microwave range is mutagenic is predominantly negative, with some positive reports. No evidence is available as to whether RFR will alter the mutagenic activity of genotoxic chemicals during a simultaneous exposure, a likely real-life situation. Two hypotheses have been proposed: a) that RFR by itself can cause mutations in a mammalian cell in vitro assay system; and b) that a simultaneous exposure to RFR during a chemical treatment of the cells with a known genotoxic agent, mitomycin C (MMC), will alter the extent of mutagenesis induced by the treatment of the cells by the chemical alone. These studies were performed using the forward mutation assay at the thymidine kinase locus in L5178Y mouse leukemic cells. The pulsed wave RFR was broadcast from an antenna horn at a frequency of 2.45 GHz. The power density was 48.8 mW/cm2 and the measured specific absorption rate (SAR) in this system was 30 W/kg (600 W forward power), which is well above current safety guidelines. The conclusions from five different experiments, employing three different concentrations of MMC, were that a) RFR exposure alone, at moderate p...Continue Reading

References

Sep 1, 1979·The Journal of Microwave Power·S K DuttaD J Brusick
Jul 9, 1987·Nature·C GabrielE Noreland
Dec 1, 1982·Biopolymers·M L Swicord, C C Davis
Jun 1, 1983·Mutation Research·D CliveK H Mavournin
May 1, 1983·Mutation Research·R D SaundersC I Kowalczuk
Jan 1, 1981·Radiation and Environmental Biophysics·M DardalhonA J Berteaud
Jan 1, 1982·Mutation Research·S N GoudV K Saxena

❮ Previous
Next ❯

Citations

Feb 17, 2001·Bioelectromagnetics·A MaesL Verschaeve
Nov 25, 2003·Bioelectromagnetics·Louis N HeynickPatrick A Mason
Jan 1, 1990·Bioelectromagnetics·M L MeltzD N Erwin
Jun 24, 1998·Mutation Research·L Verschaeve, A Maes
Jan 1, 1992·Food Additives and Contaminants·S M JickellsJ Gilbert
Feb 19, 1998·Environmental Health Perspectives·M H Repacholi
Jan 7, 1998·International Journal of Radiation Biology· VijayalaxmiM A Wittler
Oct 20, 2010·Mutation Research·L VerschaeveZ Xu
Jul 16, 2005·International Journal of Radiation Biology·J E MoulderJ P McNamee
Aug 26, 1998·Environmental and Molecular Mutagenesis·D BrusickJ Preston
Jul 1, 1994·Reviews on Environmental Health·J R SalvatoreS Mehta
May 4, 2006·Radiation Research·L VerschaeveJ Juutilainen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.