PMID: 9181221Jan 1, 1997Paper

Absorbable polylactide pins versus metallic Kirschner wires in the fixation of cancellous bone osteotomies in rats

Annales Chirurgiae Et Gynaecologiae
J ViljanenP Rokkanen

Abstract

A transverse transcondylar osteotomy of the distal femur was fixed with biodegradable self-reinforced polylevolactide (SR-PLLA) pin in 42 rats and with metallic Kirschner wire in 42 rats. Consolidation of the osteotomy and periosteal callus formation was examined within standardised sample fields histologically, histomorphometrically and microradiographically one week, 3, 6, 12, 24, 36 and 48 weeks postoperatively. The intact contralateral femur served as control. From 3-week to 48-week follow-up time the total trabecular bone area of the SR-PLLA group at the osteotomy site was significantly larger in the operated femora than in the intact control femora at the corresponding site. The specimens of the Kirschner wire group showed significantly larger total bone area only at 12 weeks postoperatively as compared with the nonoperated femora. In the SR-PLLA group 28 and in the metallic group 31 osteotomies showed solid bony union. In both experimental groups the osteotomies with solid bony union showed only scantly periosteal callus formation. More abundant callus formation in both experimental groups was related to incomplete union of the osteotomy. No signs of degradation of the SR-PLLA implant could be noticed within the follow-u...Continue Reading

Related Concepts

Related Feeds

Bioremediation (ASM)

Bioremediation is the treatment and removal of harmful pollutants or contaminants through the use of microorganisms. Discover the latest research here.