Absorbable self-reinforced polylactide (SR-PLLA) rods vs rigid rods (K-wire) in spinal fusion: an experimental study in rabbits

European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Murat BezerOsman Güven

Abstract

Several clinical and experimental reports have evaluated the spinal application of bioabsorbable material for plating the anterior lumbar and cervical spine, and in anterior and posterior lumbar interbody spinal fusion. Nevertheless, the use of these materials in posterolateral interlaminar fusion has yet to be elucidated in the literature. The effects of bioabsorbable self-reinforced polylactide rod (SR-PLLA) implantation, rigid fixation (K-wire) and non-implantation with posterior interlaminar fusion were compared using a rabbit model. Twenty-four mature domestic rabbits were divided into three groups. Eight received implantation with SR-PLLA, eight with K-wire, and eight were fused without instrumentation. The animals were killed at 12 weeks and evaluated by posteroanterior radiography, manual palpation and histological examination for the presence of fusion. Successful fusion was achieved in all of the animals in both implanted groups (SR-PLLA and K-wire), whereas solid fusion was not detected in any of the specimens in the non-implanted group. Computed tomography (CT) scans were used to detect fusion mass volume. The fusion mass in the SR-PLLA implanted group had a mean volume of 1,196 mm3 +/- 167 mm3 vs 1,061 mm3 +/- 181 ...Continue Reading

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Citations

Nov 18, 2005·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·P I J M Wuisman, T H Smit
Apr 23, 2013·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Alexander M RiordanPaul A Anderson
Jul 28, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Jiajun TangJian Yang
May 9, 2016·Journal of Pharmaceutical and Biomedical Analysis·K AdamskaA Berlińska
Jul 29, 2016·International Journal of Biological Macromolecules·A M Abd El-HayDoaa A Helal
Jul 24, 2012·Clinical Spine Surgery : a Spine Publication·Kentaro YamadaHiroaki Nakamura
May 19, 2011·The Journal of Bone and Joint Surgery. British Volume·N YalçinS Ilgezdi

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