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Absorption and distribution of 5-aminosalicylic acid from its chitosan capsule degraded by colon bacteria-released enzymes in rats

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA

May 1, 2003

Guo-feng LiZhi-liang Chen

PMID: 12754121

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Abstract

To examine the absorption and distribution of 5-aminosalicylic acid (5-ASA) in rat colon after oral administration of its chitosan capsule. 5-ASA in chitosan capsules (4.8 mg per 3 capsules) were administered orally in rats via a polyethylene cannula under light ether anesthesia. The ra...read more

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Oral Cavity
Ethers
Enzymes, antithrombotic
Mesalamine
Sampling - Surgical Action
Enzymes, peripheral vasodilators
Blood Specimen
Drug or Chemical Tissue Distribution
Specimen Type - Cannula
Microbial Anatomical Capsule Structure
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Absorption and distribution of 5-aminosalicylic acid from its chitosan capsule degraded by colon bacteria-released enzymes in rats

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA

May 1, 2003

Guo-feng LiZhi-liang Chen

PMID: 12754121

DOI:

Abstract

To examine the absorption and distribution of 5-aminosalicylic acid (5-ASA) in rat colon after oral administration of its chitosan capsule. 5-ASA in chitosan capsules (4.8 mg per 3 capsules) were administered orally in rats via a polyethylene cannula under light ether anesthesia. The ra...read more

Mentioned in this Paper

Oral Cavity
Ethers
Enzymes, antithrombotic
Mesalamine
Sampling - Surgical Action

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