PMID: 3772228Nov 1, 1986Paper

Absorption of carbonyl iron

The Journal of Laboratory and Clinical Medicine
H HuebersC Finch

Abstract

The mechanism of carbonyl iron absorption has been studied in rats. Solubilization by gastric acid was a prerequisite for subsequent absorption. The slow rate of solubilization resulted in a more prolonged absorption, responsible for the low toxicity of carbonyl iron. Large doses of carbonyl iron were held for several days by the gastric mucosa of iron-deficient animals. Once it had been solubilized, the subsequent pathway of absorption by the intestinal mucosa and the amount absorbed was similar to that of ferrous ammonium sulfate.

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