Absorption of protein molecules by the small intestine of the bullfrog tadpole, Rana catesbeiana

The Journal of Experimental Zoology
K SugimotoI Nakamura

Abstract

In the tadpole of the bullfrog, Rana catesbeiana, the absorptive cells of the small intestine are characterized by the presence of invaginations of the surface plasma membrane or pinocytic vesicles in the apical cytoplasm and numerous lysosomes in the supranuclear region. These cytological features suggest that the absorptive cells may be able to ingest some macromolecules or particles. The possibility of macromolecular absorption in this animal was examined by using horseradish peroxidase (HRP) and the electron microscopic cytochemical technique. Exogenous HRP was ingested in the absorptive cells by pinocytosis and then accumulated in multivesicular bodies (MVBs) by the contribution of pinocytic vesicles to MVBs. The pinocytic vesicle changed its shape to have an inner vesicle. Some of the inner vesicles of MVBs seem to have originated from the inner vesicles of pinocytic vesicles. Almost all the MVBs in the subapical region showed HRP activity, but some of them showed no acid phosphatase (AcPase) activity; those in the supranuclear region always showed an intense AcPase activity. Therefore some of the subapical MVBs are heterophagosomes and may be joined with lysosome during the movement toward the supranuclear region. The MV...Continue Reading

References

Apr 1, 1969·The Journal of Cell Biology·D S Friend
May 1, 1967·The Journal of Cell Biology·E HoltzmanH Villaverde
Jan 9, 1970·Science·M E BeldingC G Ray
Jan 1, 1973·Zeitschrift für Zellforschung und mikroskopische Anatomie·J Noaillac-Depeyre, N Gas
Aug 1, 1965·Journal of Ultrastructure Research·T L Lentz, R J Barrnett
Mar 28, 1966·Biochimica Et Biophysica Acta·S J KlebanoffR G Luebke
Jan 1, 1969·Journal of Ultrastructure Research·A R Spurr
Jan 1, 1968·Zeitschrift für Zellforschung und mikroskopische Anatomie·T Iwai
Jan 1, 1966·Annual Review of Physiology·C De Duve, R Wattiaux
May 1, 1970·Journal of Ultrastructure Research·J M Strum, M J Karnovsky
Jul 1, 1970·The Journal of Cell Biology·M A VenkatachalamH D Fahimi
May 1, 1968·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·E Holtzman, R Dominitz
Sep 1, 1968·The Journal of Cell Biology·J G HirschZ A Cohn
Aug 1, 1969·Journal of Bacteriology·R I Lehrer
Apr 1, 1966·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·R C Graham, M J Karnovsky
Nov 1, 1967·The Journal of Cell Biology·D S Friend, M G Farquhar
Oct 1, 1950·The Journal of Experimental Medicine·K AGNER
May 1, 1965·The Journal of Cell Biology·G B GordonK G Bensch
Jan 1, 1946·The Anatomical Record·A C TAYLOR, J J KOLLROS

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Citations

May 8, 2009·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Joanna M BiazikChristopher R Murphy
Feb 1, 1984·Analytical Biochemistry·L Ambler, G E Peters
Dec 8, 2006·Molecular & Cellular Proteomics : MCP·Tomohiko HaraTesshi Yamada
Feb 1, 1985·The Journal of Experimental Zoology·K SugimotoI Nakamura

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