Absorption rate of krill oil and fish oil in blood and brain of rats

Lipids in Health and Disease
So Hyun AhnSung Hee Han

Abstract

Krill (Euphausia superba) is a small marine crustacean with a lipid content. The mechanism of Krill oil function is not clear yet and research reports on the absorption rate of the phospholipids of krill oil in the blood and brain are very poor. We studied the effect of oral short-term and long-term administration of Krill oils (KOs) on bioavailability in the blood and brain of rats. For short-term testing of fish and KO bioavailability, rats were divided into four groups: normal, fish oil (FO), Krill oil 1 (KO), and Krill oil 2 (CKO). The blood and brain were collected at 2, 4, 8, 12, 24, and 48 h after oral administration (1000 mg/rat). Five hundred milligrams of FO, KO, and CKO were orally administered daily for 2 weeks for long-term administration, and then the brain and blood were collected. Two types of KOs showed high content of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in the PL. The EPA content of CKO and KO were 41.13 and 32.49%, respectively. After short-term KO administration, KO showed a higher EPA content than CKO in the blood after 2 h. KO showed higher content of DHA than CKO even after 2 h. FO increased until 8 h, but then decreased rapidly until 12 h. Although the total unsaturated fatty acid ...Continue Reading

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Citations

Feb 8, 2019·Biological Chemistry·Chantal ChudobaAndré Kleinridders
Aug 1, 2020·Nutritional Neuroscience·Sian EgertonCatherine Stanton
Nov 30, 2018·The Journal of Obstetrics and Gynaecology Research·Ilkin YeralOzcan Erel
Mar 12, 2020·Food Research International·Mari UyedaPatricia de Oliveira Carvalho
Nov 21, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Bo-Ram Na, Jeung-Hee Lee
Dec 16, 2020·Comprehensive Reviews in Food Science and Food Safety·Mirja Kaizer AhmmedAlaa El-Din Bekhit

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Methods Mentioned

BETA
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