Abundant genetic variability in Drosophila simulans for hybrid female lethality in interspecific crosses to Drosophila melanogaster

Genetics Research
Pierre R Gérard, Daven C Presgraves

Abstract

Intrinsic postzygotic reproductive isolation is thought to result from the substitution of multiple harmless or beneficial genetic differences between species that are incidentally deleterious when combined in species hybrids, causing hybrid sterility or inviability. Genetic variability for hybrid sterility or inviability phenotypes is, however, rarely assessed in natural populations. Here, we assess variation for Drosophila simulans-encoded maternal factor(s) that cause lethality in D. simulans-Drosophila melanogaster F(1) hybrid females. First, we survey genetic variability in the strength of D. simulans-mediated maternal effect hybrid lethality among 37 geographic and laboratory isolates. We find abundant variability in the strength of maternal effect hybrid lethality, ranging from complete lethality to none. Second, we assess maternal effect hybrid lethality for a subset of wild isolates made heterozygous with two so-called hybrid rescue strains. The results suggest that the D. simulans maternal effect hybrid lethality involves a diversity of alleles and/or multiple loci.

References

Jul 1, 1991·Current Genetics·M BukenbergerT Dingermann
Sep 15, 1994·Nature·B CharlesworthW Stephan
Apr 16, 2003·Proceedings of the National Academy of Sciences of the United States of America·Daniel A BarbashJohn Roote
Aug 4, 2004·Molecular Phylogenetics and Evolution·Matthew D Dean, J William O Ballard
Oct 24, 2006·Molecular Ecology·Gerhard Schöfl, Christian Schlötterer
Nov 25, 2006·Science·Nicholas J BrideauDaniel A Barbash
Aug 31, 1979·Science·T K Watanabe, M Kawanishi
Jun 26, 2010·Annals of Botany·Loren H Rieseberg, Benjamin K Blackman
Sep 22, 2010·Genetics·Daniel A Barbash
Dec 14, 2011·Trends in Ecology & Evolution·Asher D Cutter

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Citations

Aug 1, 2014·Ecology and Evolution·Emmanouil Dokianakis, Emmanuel D Ladoukakis
Jun 13, 2014·Journal of Evolutionary Biology·D R MatuteG Liu
Jan 28, 2017·BMC Evolutionary Biology·Ashley SaulsberryRobert M Brucker

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