Academic achievement and schizophrenia: a systematic meta-analysis.

Psychological Medicine
Hannah DicksonK R Laurens

Abstract

Cognitive impairments in childhood are associated with increased risk of schizophrenia in later life, but the extent to which poor academic achievement is associated with the disorder is unclear. Major databases were searched for articles published in English up to 31 December 2019. We conducted random-effects meta-analyses to: (1) compare general academic and mathematics achievement in youth who later developed schizophrenia and those who did not; (2) to examine the association between education level achieved and adult-onset schizophrenia; and, (3) compare general academic achievement in youth at-risk for schizophrenia and typically developing peers. Meta-regression models examined the effects of type of academic assessment, educational system, age at assessment, measurement of educational level attained, school leaving age, and study quality on academic achievement and education level among individuals with schizophrenia. Meta-analyses, comprising data of over four million individuals, found that: (1) by age 16 years, those who later developed schizophrenia had poorer general academic (Cohen's d = -0.29, p ⩽ 0.0001) and mathematics achievement (d = -0.23, p = 0.01) than those who did not; (2) individuals with schizophrenia w...Continue Reading

References

Sep 1, 1986·Controlled Clinical Trials·R DerSimonian, N Laird
Jan 1, 1995·European Archives of Psychiatry and Clinical Neuroscience·T J CrowA Sacker
Jun 14, 2000·BMJ : British Medical Journal·A J SuttonD R Jones
Jan 10, 2001·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D HaguenauerG Wells
Apr 10, 2002·Journal of the International Neuropsychological Society : JINS·Yaakov Stern
Sep 12, 2002·Schizophrenia Research·Mary CohenJohn Schorling
Oct 16, 2002·Psychiatry Research·Esther A E HolthausenRobert J van den Bosch
Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Oct 9, 2003·Acta Psychiatrica Scandinavica·I HellingC M Hultman
Jan 1, 1997·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·D Johnson-GreeneR Brandon
Dec 17, 2003·Psychiatry Research·Yong-Guan Ang, Hao-Yang Tan
Jan 15, 2005·The International Journal of Social Psychiatry·Rosemarie MallettBryan Corridan
Jun 2, 2005·Schizophrenia Research·Manuel GurpeguiJose de Leon
Feb 18, 2006·Journal of Clinical and Experimental Neuropsychology·Robert M BilderJohn M Kane
Apr 17, 2008·The American Journal of Psychiatry·Kristen A WoodberryLarry J Seidman
Jul 29, 2008·Schizophrenia Bulletin·Joy WelhamJohn McGrath
Dec 9, 2008·Journal of Molecular Endocrinology·Sachie NakamichiMasato Kasuga
Mar 19, 2009·Social Psychiatry and Psychiatric Epidemiology·Siow Ann ChongJohn Wong
Jul 23, 2009·BMJ : British Medical Journal·David MoherUNKNOWN PRISMA Group
Jun 29, 2011·The British Journal of Psychiatry : the Journal of Mental Science·Agna A Bartels-VelthuisDurk Wiersma
Jul 5, 2011·Journal of Clinical Child and Adolescent Psychology : the Official Journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53·Joshua M LangbergLily Hechtman
Jul 8, 2011·Psychological Medicine·J JundongPaul Lichtenstein
Jan 4, 2012·Archives of General Psychiatry·Nomi WerbeloffMark Weiser
Jan 18, 2012·The International Journal of Social Psychiatry·Bertilee BurgessRoger C Gibson
Mar 13, 2012·International Journal of Geriatric Psychiatry·Paul D MeestersHannie Comijs
Jan 1, 2014·Journal of Psychiatric Research·Hannah DicksonKristin R Laurens
Apr 29, 2014·Schizophrenia Research·Sarah S WuErik G Willcutt
Jul 6, 2015·Psychoneuroendocrinology·Katie L NugentL Elliot Hong

❮ Previous
Next ❯

Citations

Oct 16, 2021·Translational Psychiatry·Caitlin E MurphyCynthia Shannon Weickert

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.