Acanthamoeba keratitis in a 5-year-old boy without a history of contact lens usage

Cornea
Göktuğ DemirciYusuf Cağlar

Abstract

This study was designed to report a case of acanthamoeba keratitis in a 5-year-old child without a history of trauma or contact lens usage. The history, clinical presentation, diagnostic, and therapeutic approaches were reviewed. A 5-year-old child without any history of trauma or contact lens use was referred to our university clinic with an initial diagnosis of disciform herpetic keratitis. After 2 weeks of antibacterial and antiviral therapy, a corneal biopsy was performed for diagnostic purposes. The biopsy revealed acanthamoeba. Subsequently intensive therapy with chlorhexidine diacetate 0.02%, ketoconazole tb, hexamidine di-isethionate 0.1% was initiated. At the end of the first month, topical prednisolone acetate 1% was added to reduce inflammation, Chlorhexidine diacetate 0.02% and oral ketoconazole were discontinued, and hexamidine di-isethionate 0.1% was lowered to 4 x 1 and was administered for an additional 4 months. At the end of 5 months, all medications were withdrawn and amblyopia treatment was started. When dealing with keratitis in children, acanthamoeba should be considered even without history of contact lens usage or trauma.

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Citations

Oct 3, 2006·Parasitology Research·Hatice ErtabaklarJulia Walochnik
May 15, 2007·Current Opinion in Infectious Diseases·Philip Aloysius Thomas, Pitchairaj Geraldine
Nov 28, 2007·Antimicrobial Agents and Chemotherapy·Ursula FürnkranzJulia Walochnik
May 30, 2013·Investigative Ophthalmology & Visual Science·Jolene Chang RudellMin Zhao
Jan 24, 2014·Case Reports in Ophthalmological Medicine·Goktug Demirci, Akif Ozdamar
Apr 28, 2007·Ophthalmic Epidemiology·Youhanna W IbrahimIan A Cree
Sep 22, 2007·Journal of Receptor and Signal Transduction Research·Muh-Chiou LinChung-Ren Jan
Jul 16, 2016·PLoS Neglected Tropical Diseases·Mohammed Essa Marghany TolbaSumio Sugano
Feb 22, 2008·Journal of Medical Microbiology·Soykan OzkocJulia Walochnik
Apr 18, 2020·Journal of Water and Health·İlknur KoyunPanagiotis Karanis
Dec 17, 2014·The Journal of Immunology : Official Journal of the American Association of Immunologists·Amol SuryawanshiNoorjahan Panjwani

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