Acanthamoeba keratitis

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
N SzentmáryB Seitz

Abstract

The typical clinical appearance of acanthamoeba keratitis includes pseudodendritic epitheliopathy, perineuritis, ring infiltrates or multifocal stromal infiltrates and in some cases limbitis with infiltration of the conjunctiva and/or sterile anterior uveitis. In 83-93 % of cases of acanthamoeba keratitis the patients were contact lens wearers. Acanthamoeba keratitis is diagnosed by polymerase chain reaction (PCR), confocal biomicroscopy, in vitro cultivation and histopathological examination. Information on reliability and efficacy of conservative and surgical therapy of acanthamoeba keratitis has only been published in case series but not yet verified through randomized controlled clinical studies. After early diagnosis acanthamoeba keratitis can often be successfully treated using triple topical therapy with polyhexamide, propamidine isethionate and neomycin. Topical therapy should be continued for up to 1 year. In therapy-resistant cases cryotherapy, amniotic membrane transplantation, crosslinking therapy and therapeutic keratoplasty can be performed. The prognosis of keratoplasty following acanthamoeba keratitis is more favorable if there were no signs of infection at least 3 months before surgery.

References

Feb 1, 1992·Ophthalmology·D F LarkinJ K Dart
Oct 1, 1986·Ophthalmology·M B MooreJ B Robin
Oct 1, 1985·The British Journal of Ophthalmology·P WrightB R Jones
Dec 28, 1974·Lancet·J NagintonA D Steele
Sep 1, 1995·Archives of Ophthalmology·G D'AversaW T Driebe
Mar 1, 1994·Cornea·J G BrooksP R Badenoch
Feb 1, 1996·American Journal of Ophthalmology·D R PfisterE J Holland
Feb 1, 1996·American Journal of Ophthalmology·W D MathersR G Elgin
Oct 1, 1995·Ophthalmology·H D PerryA J Kanellopoulos
Jan 22, 1998·Cornea·M J Mannis
Jan 22, 1998·Cornea·D A SchaumbergM R Dana
Feb 4, 1999·The British Journal of Ophthalmology·C F RadfordJ K Dart
Jun 18, 1999·American Journal of Ophthalmology·S P Amoils, C Heney
Sep 27, 2000·The British Journal of Ophthalmology·S SharmaG N Rao
Jun 29, 2004·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·I ClaerhoutPh Kestelyn
Jun 28, 2005·Investigative Ophthalmology & Visual Science·Daniel W ClarkeJerry Y Niederkorn
Sep 16, 2005·Eye & Contact Lens·Kathleen Watt, Helen A Swarbrick
Jun 29, 2006·Klinische Monatsblätter für Augenheilkunde·T Reinhard, W Behrens-Baumann
Jul 18, 2006·Eye & Contact Lens·Patrick S KelleyH Dwight Cavanagh
Aug 11, 2006·Current Opinion in Ophthalmology·Kristin M Hammersmith
Jan 17, 2007·Eye & Contact Lens·Shady T AwwadH Dwight Cavanagh
Jul 31, 2007·American Journal of Ophthalmology·Nisha R AcharyaTodd P Margolis
May 1, 2009·Journal of Clinical Microbiology·Stephanie P JohnstonGovinda Visvesvara
May 5, 2009·Ophthalmology·Anna S KitzmannMichael D Wagoner
May 8, 2009·Cornea·F R S CarvalhoDenise de Freitas
Aug 8, 2009·American Journal of Ophthalmology·John K G DartSimon Kilvington
Sep 3, 2009·Clinical & Experimental Ophthalmology·Dipika V Patel, Charles N J McGhee
Apr 30, 2010·The Ocular Surface·Noorjahan Panjwani
Mar 5, 2011·Klinische Monatsblätter für Augenheilkunde·C Meltendorf, G Duncker
Oct 14, 2011·Cornea·Catherine E OldenburgJeremy D Keenan
Feb 22, 2012·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·N SzentmáryB Seitz
May 18, 2012·Klinische Monatsblätter für Augenheilkunde·N SzentmáryB Seitz

❮ Previous
Next ❯

Citations

Apr 3, 2015·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·L DaasB Seitz
May 31, 2017·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Loay DaasBerthold Seitz
Mar 6, 2019·Acta Microbiologica Et Immunologica Hungarica·Erika OroszNóra Szentmáry
Nov 27, 2019·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·J PaschaN Ardjomand

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Related Papers

Klinische Monatsblätter für Augenheilkunde
N SzentmáryB Seitz
Bulletin de la Société belge d'ophtalmologie
I Claerhout, P Kestelyn
The CLAO Journal : Official Publication of the Contact Lens Association of Ophthalmologists, Inc
A L SaliernoWilliam T Driebe
Bulletin de la Société belge d'ophtalmologie
E Draulans, P C Maudgal
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
M KlüppelB Daicker
© 2021 Meta ULC. All rights reserved