Acaricidal efficacy against cattle ticks and acute oral toxicity of Lippia javanica (Burm F.) Spreng

Tropical Animal Health and Production
James MadzimureBrighton M Mvumi

Abstract

In search for low-cost, safe and environmentally benign plant-based alternatives to commercial pesticides, the efficacy of Lippia javanica aqueous leaf extracts in controlling ticks on cattle, acute oral toxicity in mice and phytochemistry were evaluated. L. javanica aqueous leaf extracts at 10% and 20% w/v were effective at controlling cattle ticks but not as good as an amitraz-based acaricide Tickbuster. However, they can provide an effective tick control option where synthetic products are unavailable or unaffordable, particularly in remote parts of southern Africa. Peripheral blood samples collected showed no haemoparasites in treated cattle implying that animals did not suffer from clinical tick-borne diseases. The leaf aqueous extracts of L. javanica were tested for toxicity in BALB/c mice. While anecdotal evidence suggests L. javanica has low mammalian toxicity, within 48 h all mice fed with the L. javanica leaf aqueous extract at 12.5-37.5% v/v were lethargic, and overall mortality was 37.5% (n = 24). Thus, despite their apparent safety, water extracts of L. javanica leaves may have deleterious health implications on humans and animals if consumed at very high doses. Many compounds have been identified from L. javanica ...Continue Reading

References

Dec 1, 1988·Statistics in Medicine·R T O'Neill
Jun 1, 1985·Planta medica·B K NoamesiS O Bamgbose
Jun 1, 1985·Planta medica·B K NoamesiS O Bamgbose
Mar 30, 2001·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Steven R BelmainP Golob
Jul 13, 2001·Journal of Ethnopharmacology·M E PascualA Villar
Jan 1, 1983·Veterinary Clinical Pathology·J G ZinklG K Saunders
Sep 24, 2004·Phytochemistry·Nkhumeleni Jeoffrey ManenzheTeunis van Ree
Aug 20, 2005·Journal of the South African Veterinary Association·S E BizimenyeraJ N Eloff
Apr 10, 2007·Microbiological Research·Shazia N AslamDavid R Hall
Nov 21, 2007·Pest Management Science·Murray B Isman
Jun 26, 2008·Journal of Ethnopharmacology·B-E van Wyk
Sep 10, 2008·Natural Product Research·Silva F MujovoN Lall
Sep 23, 2009·Journal of Agricultural and Food Chemistry·Philip C StevensonNigel C Veitch
Oct 10, 2009·Proceedings of the National Academy of Sciences of the United States of America·Douglas J Futuyma, Anurag A Agrawal

Citations

Apr 12, 2016·Journal of Parasitic Diseases : Official Organ of the Indian Society for Parasitology·Binod Kumar, Srikanta Ghosh
Apr 9, 2014·Veterinary Parasitology·Rao Z AbbasZafar Iqbal
Jan 23, 2013·Veterinary Parasitology·Elizangela Mércia de Oliveira CruzArie Fitzgerald Blank
May 1, 2015·Journal of Ethnobiology and Ethnomedicine·Emmanuel Tendai NyahangareTonderai Mutibvu
Mar 20, 2012·Veterinary Parasitology·Timea KissMarina Spînu
Mar 18, 2011·Malaria Journal·Marta Ferreira Maia, Sarah J Moore
May 31, 2018·Experimental & Applied Acarology·Olubukola T AdenubiVinny Naidoo
Sep 5, 2013·MBio·Simon J AnthonyW Ian Lipkin
Jan 5, 2020·Tropical Animal Health and Production·Archibold G BakareJames Madzimure
Aug 4, 2018·Experimental & Applied Acarology·V O VasconcelosE R Duarte
Feb 20, 2016·Tropical Animal Health and Production·Jackson MuyobelaEnala Tembo Mwase
Mar 5, 2013·Tropical Animal Health and Production·James MadzimureBrighton M Mvumi

Related Concepts

Related Feeds

Babesiosis

Babesiosis is caused by parasites of the genus babesia, which are transmitted in nature by the bite of an infected tick. Discover the latest research on babesiosis here.