PMID: 11604586Oct 18, 2001Paper

Accelerated atherosclerosis in systemic lupus erythematosus: implications for patient management

Current Opinion in Rheumatology
J E Salmon, M J Roman

Abstract

One of the most compelling clinical challenges in the management of systemic lupus erythematosus (SLE) is the high incidence of atherosclerotic cardiovascular disease (ASCVD). Potential mechanisms for accelerated atherosclerosis in SLE include chronic inflammation, excess of traditional risk factors, and corticosteroid therapy. Given the high prevalence of atherosclerosis in SLE patients relative to young women in the general population, we propose that the presence of SLE constitutes a sufficiently potent risk factor for ASCVD to warrant more aggressive goals for risk factor reduction and strategies to reduce inflammation.

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Citations

Apr 4, 2007·Rheumatology International·Karen H CostenbaderElizabeth W Karlson
Aug 31, 2012·Journal of Thrombosis and Thrombolysis·Suman B ThapamagarDaniel Mascarenhas
Dec 19, 2003·The New England Journal of Medicine·Mary J RomanJane E Salmon
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Apr 3, 2012·The Journal of Rheumatology·Igor KarpJohn M Esdaile
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Jun 4, 2019·European Journal of Hospital Pharmacy. Science and Practice·Yang YuJiake He
Dec 3, 2003·Postgraduate Medicine·Maria Dall'Era, John C Davis
Aug 19, 2004·Cardiology in Review·Mohammed Abusamieh, Julia Ash
Aug 30, 2019·Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia·Mohamed A El-GamasyHanaa Hossney Elsaid
Oct 23, 2001·Arthritis and Rheumatism·M D LockshinM J Roman
Jan 8, 2020·Arthritis Care & Research·Shivani GargSarah E Panzer

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