PMID: 42546Nov 1, 1979

Accelerated fall in serum bromide level after administration of perchlorate to man

European Journal of Clinical Pharmacology
S Seyfert

Abstract

Five patients intoxicated with bromoureide showed accelerated elimination of bromide from serum after a single dose of perchlorate. It was probably due to increased renal excretion of bromide. Perchlorate has been reported to increase the renal clearance of other monovalent anions by inhibiting their tubular reabsorption and a similar interaction between perchlorate and bromide is suggested. Although perchlorate effectively eliminates bromide it should not replace chloride in the treatment of bromide intoxication, because of the side effects of its repeated administration.

References

Jan 1, 1975·Toxicology·A G Rauws, M J Van Logten
Jan 1, 1974·Klinische Wochenschrift·G GrosseT Schirop
Oct 1, 1965·Acta Endocrinologica·E SchönbaumM J Gill
Dec 1, 1967·The American Journal of Physiology·C F Funderburk, L Van Middlesworth
Dec 8, 1972·Deutsche medizinische Wochenschrift·B GrabenseeE Schröder
Jun 1, 1966·The American Journal of Physiology·J A SchaferE S Brubacher
May 1, 1958·The American Journal of Physiology·N S HALMIR G STUELKE
Dec 1, 1959·The International Journal of Applied Radiation and Isotopes·M ANBARZ LEWITUS
Jan 1, 1964·Physiological Reviews·J WOLFF
Jun 1, 1965·The American Journal of Physiology·M WALSER, W J RAHILL
Nov 1, 1950·The American Journal of Physiology·R L WOLF, G S EADIE

Related Concepts

Bromides
Depression, Chemical
Half-Life
Perchlorates
Carmol

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Congenital Hyperinsulinism

Congenital hyperinsulinism is caused by genetic mutations resulting in excess insulin secretion from beta cells of the pancreas. Here is the latest research.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Epigenetic Memory

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Femoral Neoplasms

Femoral Neoplasms are bone tumors that arise in the femur. Discover the latest research on femoral neoplasms here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Related Papers

Journal of Clinical Chemistry and Clinical Biochemistry. Zeitschrift Für Klinische Chemie Und Klinische Biochemie
T M Al-Khayat, F T Abdel Aziz
© 2021 Meta ULC. All rights reserved