PMID: 42546Nov 1, 1979

Accelerated fall in serum bromide level after administration of perchlorate to man

European Journal of Clinical Pharmacology
S Seyfert


Five patients intoxicated with bromoureide showed accelerated elimination of bromide from serum after a single dose of perchlorate. It was probably due to increased renal excretion of bromide. Perchlorate has been reported to increase the renal clearance of other monovalent anions by inhibiting their tubular reabsorption and a similar interaction between perchlorate and bromide is suggested. Although perchlorate effectively eliminates bromide it should not replace chloride in the treatment of bromide intoxication, because of the side effects of its repeated administration.


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Jan 1, 1974·Klinische Wochenschrift·G GrosseT Schirop
Oct 1, 1965·Acta Endocrinologica·E SchönbaumM J Gill
Dec 1, 1967·The American Journal of Physiology·C F Funderburk, L Van Middlesworth
Dec 8, 1972·Deutsche medizinische Wochenschrift·B GrabenseeE Schröder
Jun 1, 1966·The American Journal of Physiology·J A SchaferE S Brubacher
May 1, 1958·The American Journal of Physiology·N S HALMIR G STUELKE
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Jan 1, 1964·Physiological Reviews·J WOLFF
Jun 1, 1965·The American Journal of Physiology·M WALSER, W J RAHILL
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