Accelerated Long-Term Forgetting Limited to the Recollection Component of Recognition Memory in a Temporal Lobe Epileptic Patient

Neurocase
Giovanni Augusto CarlesimoCarlo Caltagirone

Abstract

Accelerated long-term forgetting (ALF) is a frequent finding in patients with temporal lobe epilepsy (TLE). Here we report the case of a TLE patient who complained of marked difficulties in remembering personal events and information even though repeated neuropsychological assessments had failed to detect any deficit on common laboratory memory tests. The patient underwent an experimental investigation that involved estimating recollection and familiarity processes in the performance on verbal and visual recognition tests, over intervals ranging from 10 minutes to 7 days. Results showed accelerated forgetting confined to the recollection component only, which was particularly evident in the verbal test.

References

Sep 28, 1978·Nature·F A Huppert, M Piercy
Oct 27, 1997·Brain and Cognition·W B Barr
Feb 25, 2000·Brain : a Journal of Neurology·R V BlakeR A McCarthy
Apr 27, 2002·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·P CaffarraA Venneri
Oct 31, 2003·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Andrew R MayesNeil Roberts
Sep 20, 2005·Journal of Neurology, Neurosurgery, and Psychiatry·F ManesJ R Hodges
Apr 21, 2007·Neuropsychologia·Erin I Skinner, Myra A Fernandes
Aug 24, 2007·Epilepsy & Behavior : E&B·Michelle DavidsonSameer M Zuberi
Feb 29, 2008·Hippocampus·Patrizia TurrizianiGiovanni Augusto Carlesimo
Sep 18, 2010·Hippocampus·John T WixtedLarry R Squire
Mar 1, 2011·Brain : a Journal of Neurology·Eve TramoniMathieu Ceccaldi
Nov 4, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Zhuang SongLarry R Squire
Jun 13, 2012·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Marco MonacoGiovanni Augusto Carlesimo
Apr 27, 2013·Proceedings of the National Academy of Sciences of the United States of America·Ricardo InsaustiLarry R Squire
Oct 1, 2013·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Zoë FitzgeraldLaurie Miller
Mar 19, 2014·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Gemma ElliottNils Muhlert
Jul 30, 2014·Frontiers in Human Neuroscience·Rodrigo SuárezLinda J Richards
Nov 11, 2015·Seizure : the Journal of the British Epilepsy Association·Henriette J TschampaWolfgang Block
Mar 25, 2016·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Anneli CasselMichael Kopelman

❮ Previous
Next ❯

Citations

Oct 3, 2018·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Daniela SmirniPatrizia Turriziani

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.