Acceleromyographic monitoring of neuromuscular block over the orbicularis oris muscle in anesthetized patients receiving vecuronium

Journal of Clinical Anesthesia
Yuhji SaitohYoshinori Nakata

Abstract

To evaluate the level of neuromuscular block acceleromyographically over the orbicularis oris muscle. Prospective, randomized, controlled study. Operating room of a university-affiliated hospital. 36 adult, ASA physical status I and II women scheduled for mastectomy with air-oxygen-isoflurane-fentanyl anesthesia. Patients were randomized to two groups. In the orbicularis oris group (n=18), the facial nerve was stimulated and movement of the orbicularis oris muscle was measured acceleromyographically. In the control group (n=18), adduction of the thumb was quantified mechanically. Onset and recovery of neuromuscular block caused by vecuronium 0.1 mg/kg were compared between the groups. Time to onset of neuromuscular block in the orbicularis oris group was significantly shorter than in the control group (176 + or - 52 vs. 220 + or - 34 sec, mean + or - SD; P = 0.004). Times to return of the first, second, third, or fourth (T1, T2, T3, or T4) response of train-of four (TOF), and recovery of T1/control were comparable between the groups. Train-of-four ratio (T4/T1) in the orbicularis oris group was significantly higher than in the control group 50 to 120 minutes after vecuronium administration (P < 0.05). Depth of neuromuscular blo...Continue Reading

Associated Clinical Trials

References

Jan 1, 1988·Acta Anaesthesiologica Scandinavica·J Viby-MogensenH K Nielsen
Jan 1, 1982·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·S SchwartingH H Goebel
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Feb 1, 1994·British Journal of Anaesthesia·P SempleA Rodbert
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Oct 10, 2002·Acta Anaesthesiologica Scandinavica·M R GätkeJ Viby-Mogensen
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Jul 20, 2007·Acta Anaesthesiologica Scandinavica·T Fuchs-BuderUNKNOWN 8th International Neuromuscular Meeting

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Citations

Feb 24, 2016·Acta Anaesthesiologica Scandinavica·E A VegaL I Cortínez

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