Access to highly active antiretroviral therapy for injection drug users: adherence, resistance, and death

Cadernos de saúde pública
D Vlahov, D D Celentano

Abstract

Injection drug users (IDUs) continue to comprise a major risk group for HIV infection throughout the world and represent the focal population for HIV epidemics in Asia and Eastern Europe/Russia. HIV prevention programs have ranged from HIV testing and counseling, education, behavioral and network interventions, drug abuse treatment, bleach disinfection of needles, needle exchange and expanded syringe access, as well as reducing transition to injection and primary substance abuse prevention. With the advent of highly active antiretroviral therapy (HAART) in 1996, dramatic clinical improvements have been seen. In addition, the treatment's impact on reducing HIV viral load (and therefore transmission by all routes) provides a stronger rationale for an expansion of the focus on prevention to emphasize early identification and treatment of HIV infected individuals. However, treatment of IDUs has many challenges including adherence, resistance and relapse to high risk behaviors, all of which impact issues of access and ultimately effectiveness of potent antiretroviral treatment. A major current challenge in addressing the HIV epidemic revolves around an appropriate approach to HIV treatment for IDUs.

References

Oct 1, 1991·American Journal of Public Health·L SolomonJ Astemborski
Jan 1, 1991·Journal of General Internal Medicine·M D SteinC C Carpenter
Mar 1, 1988·Reviews of Infectious Diseases·R L HubbardH M Ginzburg
Sep 1, 1995·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·S L GrosecloseW J Kassler
Jan 1, 1993·Advances in Experimental Medicine and Biology·P K PetersonC C Chao
Jan 1, 1995·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·N GalaiA Muñoz
Jul 2, 1997·JAMA : the Journal of the American Medical Association·D BangsbergA R Moss
Jul 25, 1997·Drug and Alcohol Dependence·A AdesanyaO A Odejide
Nov 5, 1997·Psychiatric Services : a Journal of the American Psychiatric Association·J A KellyM I Fernandez
May 21, 1998·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·D LongshoreM D Anglin
Jun 4, 1998·Journal of Neuroimmunology·T Pellegrino, B M Bayer
Jun 27, 1998·JAMA : the Journal of the American Medical Association·M A Wainberg, G Friedland
Jul 15, 1998·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·T DiazT S Jones
Aug 26, 1998·JAMA : the Journal of the American Medical Association·D D CelentanoR D Moore
Aug 26, 1998·JAMA : the Journal of the American Medical Association·S A StrathdeeR S Hogg
Sep 12, 1998·Annals of Internal Medicine·F L Altice, G H Friedland
Dec 16, 1998·Journal of Addictive Diseases·S ShoptawR A Rawson
Dec 24, 1998·The New England Journal of Medicine·S A BozzetteM F Shapiro
Feb 24, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C L BrosgartD I Abrams
Mar 17, 1999·American Journal of Public Health·J A Kelly
Mar 17, 1999·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·P PezzottiJ Astemborski
Jul 1, 1999·JAMA : the Journal of the American Medical Association·M F ShapiroS A Bozzette
Sep 29, 1999·JAMA : the Journal of the American Medical Association·D BodenM Markowitz
Sep 29, 1999·JAMA : the Journal of the American Medical Association·S J LittleD D Richman
Dec 14, 1999·Substance Use & Misuse·M E Barrett, M P de Palo
Dec 10, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·N SinghM M Wagener
Mar 9, 2000·Drug and Alcohol Dependence·J L Sorensen, A L Copeland
Mar 14, 2000·JAMA : the Journal of the American Medical Association·J E Gallant
May 24, 2000·Drug and Alcohol Dependence·U SambamoorthiJ Walkup
Jun 24, 2000·Journal of Acquired Immune Deficiency Syndromes : JAIDS·A L GiffordS A Bozzette
Jul 6, 2000·Annals of Internal Medicine·D L PatersonN Singh

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Citations

Mar 17, 2011·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Anita PalepuEvan Wood
Jul 10, 2012·Current HIV/AIDS Reports·Michael V O'ShaughnessyJulio S G Montaner
Sep 1, 2012·Current HIV/AIDS Reports·Meredith Camp BinfordFrederick L Altice
Oct 19, 2012·Current Opinion in HIV and AIDS·Stefan D BaralChris Beyrer
Aug 14, 2009·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Monica MaltaSteffanie A Strathdee
Mar 1, 2011·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Lynn E SullivanUNKNOWN BHIVES Collaborative
Dec 3, 2011·Journal of Acquired Immune Deficiency Syndromes : JAIDS·M-J MilloyEvan Wood
Jul 30, 2009·Harm Reduction Journal·Beth S RachlisEvan Wood
Nov 21, 2008·AIDS and Behavior·Monica MaltaFrancisco I Bastos
Aug 11, 2007·The International Journal on Drug Policy·Martin C DonoghoeSrdan Matic
Sep 15, 2007·The International Journal on Drug Policy·Max Hopwood, Carla Treloar
Apr 14, 2006·Cadernos de saúde pública·Aline Dayrell FerreiraUNKNOWN Projeto AjUDE-Brasil II
Apr 14, 2006·Cadernos de saúde pública·Angelita Cristine de MeloBernard François Couttolenc
Apr 25, 2012·AIDS and Behavior·Cáritas Relva BassoMaria Ines Battistela Nemes
May 31, 2019·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Suzana MullerMário Reis Álvarez-da-Silva

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