Accidental ingestion of a zinc and copper sulfate preparation

Journal of Toxicology. Clinical Toxicology
P HantsonP Mahieu

Abstract

An 86-year-old woman accidentally ingested a preparation containing zinc and copper sulfate. At ninety minutes after ingestion, the peak plasma concentration was 1979 micrograms/dL for zinc and 209 micrograms/dL for copper, suggesting preferential absorption of zinc. The major complications were gastric and bronchial inflammation due to the corrosive properties of these compounds. Systemic manifestations also developed with cardiovascular failure and renal insufficiency, but the patient made a complete recovery. In addition to symptomatic treatment, chelation therapy with dimercaprol and D-penicillamine was given for 48 h. The available clinical and toxicokinetic data do not support the benefits of chelation in addition to supportive therapy.

References

Mar 25, 1978·British Medical Journal·R Moore
May 28, 1977·British Medical Journal·A BrocksG Glazer
Aug 1, 1979·Journal of Inorganic Biochemistry·A C HallI Bremner
Sep 1, 1977·The American Journal of the Medical Sciences·K S ChughK C Das
Feb 1, 1977·American Journal of Diseases of Children·F M WalshB J Pearson
Jan 1, 1977·Postgraduate Medical Journal·K S ChughB N Datta
Jan 1, 1975·Nephron·B N AgarwalE Labovitz
May 1, 1992·Medicine·G J Brewer, V Yuzbasiyan-Gurkan
Oct 1, 1990·Annals of Emergency Medicine·K K BurkhartB Rumack
Jan 1, 1988·Neuroradiology·W Müller-ForellP J Egan
May 1, 1987·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·G M HillD E Hartmann
Aug 1, 1986·Annals of Emergency Medicine·E Schwartz, E Schmidt
Sep 1, 1974·Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association·S R Cohen
Jan 1, 1969·The Journal of Nutrition·D R Van Campen
Nov 1, 1965·The American Journal of Medicine·H K ChuttaniD N Gupta
Jan 1, 1984·Journal of Toxicology. Clinical Toxicology·W JantschB H Rumack
Sep 1, 1983·Annals of Internal Medicine·G J BrewerP Rabbani
Feb 1, 1981·Annals of Emergency Medicine·S J Chobanian
May 1, 1981·Annals of Emergency Medicine·J L Potter
Jun 1, 1994·Annals of Emergency Medicine·P E McKinneyK Kulig
May 1, 1964·Archives of Environmental Health·M A BROWNJ JUAREZ

❮ Previous
Next ❯

Citations

Aug 26, 1998·Journal of Toxicology. Clinical Toxicology·P HantsonP Mahieu
Apr 12, 2011·Fundamental & Clinical Pharmacology·Meshal Al MoutaeryMohammad Tariq
Apr 4, 2000·Reviews on Environmental Health·F PizarroM Araya
Jun 26, 1999·Journal of Toxicology. Clinical Toxicology·D G Barceloux
Jan 25, 2003·Journal of Paediatrics and Child Health·S BlundellD Fitzgerald

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

Atrophic Gastritis

Atrophic Gastritis is a process where gastric glandular cells are lost and replaced with firbous tissues, as a result of chronic inflammation. Learn more about Atrophic Gastritis here.

Related Papers

Journal of Pediatric Surgery
A YamatakaJ Wyeth
European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
A CzłonkowskaM Czerska
Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
Chittinad Havanond
Pediatric Surgery International
Haluk CeylanAhmet Gözen
© 2021 Meta ULC. All rights reserved