PMID: 11902698Mar 21, 2002Paper

Accidental injection of epinephrine from an autoinjector: invasive treatment not always required

Southern Medical Journal
Rita MrvosEdward P Krenzelok

Abstract

Individual case reports of accidental injection with epinephrine appear in the literature and seem to represent the worst case scenarios. We present a case series of 28 exposures to epinephrine via autoinjector. All accidental parenteral injections of epinephrine by autoinjector reported to two regional poison information centers over a 2-year period were included. Injection sites included digits (23 cases), palm (4 cases), and thigh (1 case). Symptoms included swelling, pallor, pain, and erythema. Four patients reported no effect, and 9 required no treatment. Ten patients obtained relief with warm soaks, 1 patient had massage only, and 2 patients were lost to follow-up. Fourteen were examined in the emergency department, and 14 were treated at home. Although some injection injuries must be treated in an emergency facility, many can be treated at home. Immediate referral to a health care facility is not needed in all cases and at times is unwarranted.

Citations

May 16, 2009·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·F Estelle R SimonsEric S Edwards
Dec 9, 2004·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Pauline M DobsonMark Loewenthal
Feb 19, 2010·The Nurse Practitioner·Elisabeth A White
Sep 10, 2008·Hand : Official Journal of the American Association for Hand Surgery·Colleen Fitzcharles-BoweDon Lalonde
Dec 17, 2016·American Journal of Therapeutics·Marco AnshienBrandon K Wills

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