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Accounting for biases in riboprofiling data indicates a major role for proline and not positive amino acids in stalling translation

bioRxiv

Jun 11, 2014

Carlo G. Artieri, Hunter B. Fraser

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Abstract

The recent advent of ribosome profiling ? sequencing of short ribosome-bound fragments of mRNA ? has offered an unprecedented opportunity to interrogate the sequence features responsible for modulating translational rates. Nevertheless, numerous analyses of the first riboprofiling datas...read more

Mentioned in this Paper

probe gene fragment
Protein Biosynthesis
Ribosomes
Profile (Lab Procedure)
Genetic Translation Process
Proline
Peptide Biosynthesis
Yeasts
Nucleic Acid Sequencing
In Vitro [Publication Type]
19
2
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  • Accounting for biases in riboprofiling data indicates a major role for proline and not positive amino acids in stalling translation

    bioRxiv

    Jun 11, 2014

    Carlo G. Artieri, Hunter B. Fraser

    PMID: 990006221

    DOI: 10.1101/006221

    Abstract

    The recent advent of ribosome profiling ? sequencing of short ribosome-bound fragments of mRNA ? has offered an unprecedented opportunity to interrogate the sequence features responsible for modulating translational rates. Nevertheless, numerous analyses of the first riboprofiling datas...read more

    Mentioned in this Paper

    probe gene fragment
    Protein Biosynthesis
    Ribosomes
    Profile (Lab Procedure)
    Genetic Translation Process
    19
    2

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