Accounting for dominance to improve genomic evaluations of dairy cows for fertility and milk production traits

Genetics, Selection, Evolution : GSE
Hassan AlilooB J Hayes

Abstract

Dominance effects may contribute to genetic variation of complex traits in dairy cattle, especially for traits closely related to fitness such as fertility. However, traditional genetic evaluations generally ignore dominance effects and consider additive genetic effects only. Availability of dense single nucleotide polymorphisms (SNPs) panels provides the opportunity to investigate the role of dominance in quantitative variation of complex traits at both the SNP and animal levels. Including dominance effects in the genomic evaluation of animals could also help to increase the accuracy of prediction of future phenotypes. In this study, we estimated additive and dominance variance components for fertility and milk production traits of genotyped Holstein and Jersey cows in Australia. The predictive abilities of a model that accounts for additive effects only (additive), and a model that accounts for both additive and dominance effects (additive + dominance) were compared in a fivefold cross-validation. Estimates of the proportion of dominance variation relative to phenotypic variation that is captured by SNPs, for production traits, were up to 3.8 and 7.1 % in Holstein and Jersey cows, respectively, whereas, for fertility, they we...Continue Reading

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Citations

Aug 24, 2017·Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie·N Moghaddar, J H J van der Werf
Jul 23, 2018·Journal of Animal Science·Fernanda S S RaidanAntonio Reverter
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Sep 19, 2018·Genetics, Selection, Evolution : GSE·Mehdi Momen, Gota Morota
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