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Accounting for eXentricities: Analysis of the X chromosome in GWAS reveals X-linked genes implicated in autoimmune diseases

bioRxiv

Sep 21, 2014

Diana ChangAlon Keinan

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Abstract

Many complex human diseases are highly sexually dimorphic, suggesting a potential contribution of the X chromosome to disease risk. However, the X chromosome has been neglected or incorrectly analyzed in most genome-wide association studies (GWAS). We present tailored analytical methods...read more

Mentioned in this Paper

Gene Expression
Computer Software
X Chromosome
Crohn Disease
Stomach
Study
CENPI gene
FOXP3 gene
Physiological Aspects
C1GALT1C1 protein, human
11
1
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  • Accounting for eXentricities: Analysis of the X chromosome in GWAS reveals X-linked genes implicated in autoimmune diseases

    bioRxiv

    Sep 21, 2014

    Diana ChangAlon Keinan

    PMID: 990009464

    DOI: 10.1101/009464

    Abstract

    Many complex human diseases are highly sexually dimorphic, suggesting a potential contribution of the X chromosome to disease risk. However, the X chromosome has been neglected or incorrectly analyzed in most genome-wide association studies (GWAS). We present tailored analytical methods...read more

    Mentioned in this Paper

    Gene Expression
    Computer Software
    X Chromosome
    Crohn Disease
    Stomach
    11
    1

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