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Accounting for experimental noise reveals that mRNA levels, amplified by post-transcriptional processes, largely determine steady-state protein levels in yeast

bioRxiv

Sep 21, 2014

Gábor CsárdiD. Allan Drummond

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Abstract

Cells respond to their environment by modulating protein levels through mRNA transcription and post-transcriptional control. Modest observed correlations between global steady-state mRNA and protein measurements have been interpreted as evidence that mRNA levels determine roughly 40% of...read more

Mentioned in this Paper

Regulation of Translation
Protein Biosynthesis
Study
Post-Transcriptional Regulation
Metabolic Phenomena
Saccharomycetales
Yeasts
Gene Amplification Technique
RNA, Messenger
Analysis
76
1
21
Paper Details
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  • Accounting for experimental noise reveals that mRNA levels, amplified by post-transcriptional processes, largely determine steady-state protein levels in yeast

    bioRxiv

    Sep 21, 2014

    Gábor CsárdiD. Allan Drummond

    PMID: 990009472

    DOI: 10.1101/009472

    Abstract

    Cells respond to their environment by modulating protein levels through mRNA transcription and post-transcriptional control. Modest observed correlations between global steady-state mRNA and protein measurements have been interpreted as evidence that mRNA levels determine roughly 40% of...read more

    Mentioned in this Paper

    Regulation of Translation
    Protein Biosynthesis
    Study
    Post-Transcriptional Regulation
    Metabolic Phenomena
    76
    1
    21
    Paper Details
    References
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    • Citations

      References currently unavailable

      We're still populating references for this paper, please check back later.
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