Accumulation and effects of nickel and thallium in early-life stages of fathead minnows (Pimephales promelas)

Ecotoxicology and Environmental Safety
Dominique Lapointe, Patrice Couture

Abstract

Early-life stages of fathead minnows were exposed to environmentally relevant concentrations of aqueous and dietary nickel and thallium and metal accumulation was monitored from the embryo until the larvae reached 21 days after hatching. During and after metal exposure, 6 toxicity endpoints were measured: time to hatch, embryo survival rate, routine metabolic rate and the activity of key enzymes (lactate dehydrogenase, nucleoside diphosphate kinase (NDPK), cytochrome C oxidase (CCO)). Although both Ni and Tl bioaccumulation were significant in embryos and non-feeding larvae, water was the major source of Ni and Tl in feeding larvae. Exposure to aqueous Ni decreased time to hatch and increased aerobic and biosynthetic capacities (as indicated by a higher activity of CCO and NDPK, respectively), suggesting that aqueous Ni exposure stimulates metabolism in early-life stages of fathead minnows.

References

Jan 1, 1975·Bulletin of Environmental Contamination and Toxicology·V ZitkoW G Carson
Feb 24, 2001·Environmental Pollution·U BorgmannW P Norwood
May 15, 2002·Aquatic Toxicology·M D PtashynskiJ F Klaverkamp
Jul 12, 2003·Environmental Science & Technology·Benjamin S TwiningNicholas S Fisher
Feb 11, 2004·Environmental Toxicology and Chemistry·Tham Chung HoangStephen J Klaine
Sep 24, 2004·Environmental Toxicology and Chemistry·Kevin V BrixJim Laughlin
Jun 1, 2005·Ecotoxicology and Environmental Safety·Gregory G PylePatrice Couture
Feb 15, 1991·Science·J R Reinfelder, N S Fisher
Mar 3, 2009·Archives of Environmental Contamination and Toxicology·Dominique Lapointe, Patrice Couture

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.