Accumulation of 19 environmental phenolic and xenobiotic heterocyclic aromatic compounds in human adipose tissue

Environment International
Lei WangKurunthachalam Kannan

Abstract

The extensive use of environmental phenols (e.g., bisphenol A) and heterocyclic aromatic compounds (e.g., benzothiazole) in consumer products as well as widespread exposure of humans to these compounds have been well documented. Biomonitoring studies have used urinary measurements to assess exposures, based on the assumption that these chemicals are metabolized and eliminated in urine. Despite the fact that some of these chemicals are moderately lipophilic, the extent of their accumulation in adipose fat tissues has not been convincingly demonstrated. In this study, human adipose fat samples (N=20) collected from New York City, USA, were analyzed for the presence of environmental phenols, including bisphenol A (BPA), benzophenone-3 (BP-3), triclosan (TCS), and parabens, as well as heterocyclic aromatic compounds, including benzotriazole (BTR), benzothiazole (BTH), and their derivatives. BPA and TCS were frequently detected in adipose tissues at concentrations (geometric mean [GM]: 3.95ng/g wet wt for BPA and 7.21ng/g wet wt for TCS) similar to or below the values reported for human urine. High concentrations of BP-3 were found in human adipose tissues (GM: 43.4; maximum: 4940ng/g wet wt) and a positive correlation between BP-3 ...Continue Reading

References

Sep 1, 1985·Archives of Environmental Contamination and Toxicology·J B FerrarioR E Tracy
Jan 6, 1999·Toxicology and Applied Pharmacology·E J RoutledgeJ P Sumpter
Jul 20, 2001·Marine Environmental Research·C M ForanW H Benson
Feb 28, 2002·The Journal of Steroid Biochemistry and Molecular Biology·J R ByfordP D Darbre
Jul 12, 2002·Archives of Toxicology·Shinshi Oishi
Oct 22, 2002·Chemical Research in Toxicology·Wolfgang VölkelWolfgang Dekant
May 6, 2003·Toxicological Sciences : an Official Journal of the Society of Toxicology·Risheng MaMargret Schlumpf
Apr 19, 2005·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·M G SoniG A Burdock
Aug 9, 2005·Environmental Science & Technology·Boris Johnson-RestrepoBruce D Rodan
Aug 11, 2007·Reproductive Toxicology·M F FernandezN Olea
Sep 11, 2007·Reproductive Toxicology·Laura N VandenbergWade V Welshons
Jan 23, 2009·Occupational and Environmental Medicine·T Sorahan
May 30, 2009·Environmental Health Perspectives·Richard W StahlhutShanna H Swan
Mar 27, 2010·Environmental Health Perspectives·Laura N VandenbergGilbert Schoenfelder
Apr 13, 2010·Reproductive Toxicology·Julie BobergUlla Hass
Jul 30, 2011·Journal of Toxicology and Environmental Health. Part a·Gary GinsbergTara Kurland
Aug 9, 2011·Toxicology and Applied Pharmacology·Daniel R DoergeJeffrey W Fisher
Dec 20, 2011·Environmental Toxicology and Chemistry·Manmeet W PannuGurpal S Toor
Mar 9, 2012·Environmental Health Perspectives·Robin E DodsonRuthann A Rudel
Mar 16, 2012·Environmental Science & Technology·Tatsuya KunisueKurunthachalam Kannan
Dec 6, 2012·Analytical Chemistry·Alexandros G AsimakopoulosKurunthachalam Kannan
Aug 6, 2013·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Ebru KarpuzogluRobert M Gogal

❮ Previous
Next ❯

Citations

Aug 19, 2015·The Science of the Total Environment·Yanjian WanKurunthachalam Kannan
Mar 10, 2016·Journal of Hazardous Materials·Yanjian WanKurunthachalam Kannan
Nov 20, 2015·Ecotoxicology and Environmental Safety·Fanxing ZengNiels C Bols
Feb 26, 2016·Chemical Research in Toxicology·Rocio Castillo SanchezEduardo Perez Salazar
Sep 18, 2015·Environmental Science & Technology·Jingchuan XueKurunthachalam Kannan
Jul 15, 2015·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Nataša MilićMilica Medić-Stojanoska
Jul 15, 2016·BioMed Research International·Fernando Barbosa JuniorDaniel Cyr
Oct 11, 2016·SpringerPlus·L W B OlaniyanA I Okoh
Dec 14, 2016·Environmental Science & Technology·Xiaohong XueKurunthachalam Kannan
Sep 14, 2017·International Journal of Environmental Research and Public Health·Thomas P van der MeerJana V van Vliet-Ostaptchouk
Aug 2, 2019·Toxicological Sciences : an Official Journal of the Society of Toxicology·Pomierny BartoszBudziszewska Bogusława
Aug 30, 2019·Environmental Science and Pollution Research International·Selen DoganTayup Simsek
Apr 1, 2020·Sensors·Alessandra MuschiettiJosé Manuel Díaz-Cruz
Feb 6, 2020·Journal of Epidemiology and Community Health·Vicente Mustieles, Juan P Arrebola
Apr 23, 2020·Toxicological Sciences : an Official Journal of the Society of Toxicology·Lisa M WeatherlyStacey E Anderson
Jul 30, 2020·International Journal of Toxicology·Priya CherianBart Heldreth
Dec 12, 2018·Frontiers in Molecular Neuroscience·Alejandra Arias-CavieresGenaro Barrientos
Apr 23, 2019·Neurotoxicity Research·Żaneta BroniowskaBogusława Budziszewska
May 31, 2018·Scientific Reports·Pantelis CharisiadisJana V van Vliet-Ostaptchouk
Jul 19, 2018·Journal of Exposure Science & Environmental Epidemiology·Mahsa M YazdySusan A Korrick
Feb 12, 2020·Journal of Exposure Science & Environmental Epidemiology·Qiuping WenWei Xia
Oct 22, 2020·Bulletin of Environmental Contamination and Toxicology·Sylvia M Cacua-OrtizGustavo A Peñuela
Nov 11, 2020·Journal of Applied Toxicology : JAT·Abdullah Farasani, Philippa D Darbre
Oct 13, 2020·The Science of the Total Environment·Xiaoliang LiaoZongwei Cai
Oct 11, 2020·The Science of the Total Environment·Yanran HuangKelvin Sze-Yin Leung
Oct 13, 2020·Environmental Research·Thomas P van der MeerJana V van Vliet-Ostaptchouk
Mar 28, 2018·International Journal of Hygiene and Environmental Health·Lesliam Quirós-AlcaláMeleah Boyle
Apr 17, 2021·Environmental Science and Pollution Research International·Lu-Lu JiaYing Guo
Jun 3, 2021·International Journal of Molecular Sciences·Isabel C CohenSonya M Schuh

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.