PMID: 108243Mar 1, 1979

Accumulation of iron by yersiniae

Journal of Bacteriology
R D Perry, Robert R Brubaker


Escherichia coli, Bacillus megaterium, and three species of yersiniae grew rapidly without significant production of soluble siderophores in a defined iron-sufficient medium (20 microM Fe3+). In iron-deficient medium (0.1 to 0.3 microM Fe3+) all organisms showed reduced growth, and there was extensive production of siderophores by E. coli and B. megaterium. Release of soluble siderophores by Yersinia pestis, Y. pseudotuberculosis, or Y. enterocolitica in this medium was not detected. Citrate (1 mM) inhibited growth of yersiniae in iron-deficient medium, indicating that the organisms lack an inducible Fe3+-citrate transport mechanism. Uptake of 59Fe3+ by all yersiniae was an energy-dependent saturable process, showing increased accumulation after adaptation to iron-deficient medium. Growth of Y. pseudotuberculosis and Y. enterocolitica but not Y. pestis on iron-limited solid medium was enhanced to varying degrees by exogenous siderophores (desferal, schizokinen, aerobactin, and enterochelin). Only hemin (0.1 pmol) or a combination of inorganic iron plus protoporphyrin IX promoted growth of Y. pestis on agar rendered highly iron deficient with egg white conalbumin (10 microM). Growth of Y. pseudotuberculosis and Y. enterocolitica...Continue Reading


Mar 1, 1990·FEMS Microbiology Reviews·J L MartinezF Baquero
Mar 1, 1990·FEMS Microbiology Letters·D AbeckO Braun-Falco
Oct 1, 1988·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·V de Lorenzo, J L Martinez
Aug 14, 1982·British Medical Journal·K MelbyS A Nordbø
Feb 16, 2005·The Journal of Biological Chemistry·Mollie D WinfieldEduardo A Groisman
Sep 1, 1992·Molecular Microbiology·T M Staggs, R D Perry
May 1, 1989·The British Journal of Surgery·S E AttwoodF B Keane
Jan 1, 1991·Biology of Metals·M L Pendrak, R D Perry
Sep 1, 1991·The Australian and New Zealand Journal of Surgery·T B Elliott, B W Partridge
Nov 1, 1993·FEMS Microbiology Reviews·K G Wooldridge, P H Williams
Aug 1, 1991·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J J BullenH J Rogers
Jan 1, 1988·Critical Reviews in Microbiology·S M Payne
Jan 1, 1984·Scandinavian Journal of Infectious Diseases·G BjuneJ Eng
Feb 1, 1993·Molecular & General Genetics : MGG·R KoebnikK Hantke
Jun 30, 2007·Microbiology·Stanislav FormanJ D Fetherston
Sep 24, 2005·Archives of Pharmacal Research·Yongmoon Han
Aug 1, 1996·The Journal of Trauma·C G WardH J Rogers
May 1, 1993·Molecular Microbiology·M L Pendrak, R D Perry
Oct 1, 1990·Oral Microbiology and Immunology·P K BaruaM E Neiders
Jan 1, 1988·FEMS Microbiology Immunology·J H BrockG J Kontoghiorghes
Jan 1, 1988·Australian Veterinary Journal·R B CallinanD B Unger
May 9, 2000·Clinical and Diagnostic Laboratory Immunology·S Schubert, I B Autenrieth
Jan 1, 1985·Journal of Basic Microbiology·K D FlossmannH Rosner
Jun 4, 2002·DNA and Cell Biology·Igor Stojiljkovic, Donna Perkins-Balding
Mar 21, 2009·PLoS Genetics·J Christian PerezEduardo A Groisman
Apr 7, 2006·Archives of Pharmacal Research·Jue-Hee Lee, Yongmoon Han
Mar 3, 2009·Proceedings of the National Academy of Sciences of the United States of America·J Christian Perez, Eduardo A Groisman
Jan 1, 1992·Critical Reviews in Microbiology·B R OttoD M MacLaren
Jul 6, 1989·The New England Journal of Medicine·T L Cover, R C Aber
Nov 28, 2012·Biochemical Society Transactions·Petra LukacikSusan K Buchanan
Oct 1, 1987·Drug Intelligence & Clinical Pharmacy·S M Eggleston
Dec 6, 2006·Annals of Saudi Medicine·Ahmed H Al-SalemMona Al Nazer

Related Concepts

Bacillus megaterium
Alkalescens-Dispar Group
Yersinia <bacteria>

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Systemic Juvenile Idiopathic Arthritis

Systemic juvenile idiopathic arthritis is a rare rheumatic disease that affects children. Symptoms include joint pain, but also fevers and skin rashes. Here is the latest on this disease.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Pontocerebellar Hypoplasia

Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.

Cell Atlas Along the Gut-Brain Axis

Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.

Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease that occurs in individuals that suffer repetitive brain trauma. Discover the latest research on traumatic encephalopathy here.