Accumulation of protoporphyrin isomers I and III, and multiple decarboxylation products of uroporphyrin in a case of porphyria in a slaughtered pig

Zentralblatt für Veterinärmedizin. Reihe A
S RoelsJ Hoorens

Abstract

Pathological and biochemical examinations were made on tissues from a case of porphyria in a slaughtered pig. Bones, kidneys, teeth and lymph nodes showed a mahogany discoloration. Histologically, the pigment was negative on staining for iron (Gomori) and showed a strong red-orange fluorescence under UV light proving it to be porphyrin. Biochemical studies on the kidney, lymph nodes, bone and bone marrow revealed a 'mixed' erythropoietic protoporphyria-coproporphyria. This indicates that the case presented probably represented both a uroporphyrinogen decarboxylase and uroporphyrinogen-III-cosynthase dysfunction.

References

May 1, 1983·The Biochemical Journal·C K LimD J Wright
Jun 1, 1980·Nihon juigaku zasshi. The Japanese journal of veterinary science·C YamashitaR Ishitani
Jul 23, 1955·Nature·S K JØRGENSEN, T K WITH

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Citations

Jan 7, 2006·The Journal of Veterinary Medical Science·Yutaka UedaSatoshi Nakahara
Feb 8, 2005·Neuromuscular Disorders : NMD·G Diane Shelton, Eva Engvall
Jan 1, 2008·Journal of Immigrant and Minority Health·Hikmet JamilHaifa Fakhouri
Jul 5, 2013·Journal of the American Veterinary Medical Association·Famke AeffnerPaul Stromberg
Nov 24, 2020·Journal of the American Veterinary Medical Association·Brittany C KunzKarl E Anderson
Apr 29, 1998·Clinics in Dermatology·B C Tennant

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