PMID: 11924753Apr 2, 2002Paper

Accuracy and clinical utility of dialysis dose measurement using online ionic dialysance

Clinical Nephrology
K P Katopodis, N A Hoenich

Abstract

Statistical associations between urea removal and survival have been described in a number of publications. Urea removal during treatment may be quantified by the delivered dose of dialysis. Methods in clinical use to measure delivered dose are retrospective and reliant on accurate blood sampling. The new generation of single patient proportionating systems incorporate the facility to automatically measure ionic dialysance throughout dialysis. In a prospective study on 9 anuric patients with a stable dialysis prescription, we have compared the agreement of the dose of dialysis determined from ionic dialysance (Dt/V) with that derived from equilibriated Kt/V (eKt/V) and Kt/V measured by direct dialysis quantification (Kt/V(DDQ)) using 2 types of hemodialysis membrane (hemophan and low-flux polysulfone). The variability of the delivered dose over a 1-month period was also determined. Ionic dialysance was independent of membrane type. It was comparable to that established for plasma urea water clearance for hemophan but lower for polysulfone (p < 0.001). The mean (+/- SD) delivered dose of dialysis (Dt/V) was similar for both membranes (1.18 +/- 0.15 (hemophan) and 1.18 +/- 0.11 (low-flux polysulfone)). Bland Altman comparisons sh...Continue Reading

Citations

Mar 23, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Waclaw WeydeMarian Klinger
Nov 8, 2014·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Carlo Basile, Daniel Schneditz
Aug 24, 2011·Blood Purification·Peter AhrenholzRalf Wojke
Mar 19, 2014·The International Journal of Artificial Organs·Taoufiq AatifZouhair Oualim
Oct 18, 2003·Current Opinion in Nephrology and Hypertension·Stewart H Lambie, Christopher W McIntyre
Jan 24, 2004·The International Journal of Artificial Organs·R Rault
Apr 30, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Rachel C CarsonJennifer M MacRae

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