PMID: 6402198Feb 26, 1983Paper

Accuracy and value of the Hemoccult test in symptomatic patients

British Medical Journal
R J LeicesterR H Hunt

Abstract

Hemoccult faecal occult blood testing is widely advocated as a screening test for colorectal cancer but few studies have shown its correlation with conventional methods of investigation for colorectal disease. In a prospective study of 802 symptomatic patients with suspected colorectal disease there was good patient compliance (92.5%) and a high specificity for colorectal cancer (85.4%). The false positive rate was 8.6% (12 of 140 patients with positive results), and while the test result was positive in 22 of 26 colonic cancers the false negative rate for rectal cancer (45.4%) should not detract from its value as a screening test if proper digital anorectal and proctosigmoidoscopic examination are widely practised. A positive Hemoccult test result is a useful indicator for the need to proceed to full colorectal investigation, including colonoscopy.

References

Jun 24, 1978·Lancet·R H TeagueA E Read
Dec 16, 1978·British Medical Journal·E T SwarbrickC B Williams
Jan 1, 1978·The British Journal of Surgery·P G Gill, P J Morris
Jan 2, 1982·Lancet·R J LeicesterR J Nicholls
Mar 15, 1980·Cancer·S J Winawer
Feb 16, 1980·British Medical Journal·D N ClarkeC D Needham
Apr 10, 1982·British Medical Journal

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Citations

May 1, 1986·Digestive Diseases and Sciences·R G Norfleet
Dec 1, 1984·Diseases of the Colon and Rectum·S D WexnerW A Wichern
May 26, 2010·Journal of General Internal Medicine·Alan S Rosman, Mark A Korsten
Mar 9, 1985·British Medical Journal·I P DonaldS P Wilkinson
Dec 19, 2006·Journal of Clinical Pathology·W S A SmellieC van Heyningen
Nov 1, 1989·Journal of the American Academy of Dermatology·M GraffeoA Paterlini
Dec 1, 1991·Journal of the American Geriatrics Society·S E KlosJ S Goodwin
Jan 1, 1989·Medical Decision Making : an International Journal of the Society for Medical Decision Making·W L EnglandV B Hunt
Jun 5, 2003·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M.R. Thompson
Dec 3, 2016·Current Protocols in Mouse Biology·Stacey J Sukoff Rizzo, Jill L Silverman
Jun 26, 1993·BMJ : British Medical Journal·I Maclennan, J Hill
Jan 1, 1994·International Journal of Technology Assessment in Health Care·T ShimboJ M Eisenberg
Apr 1, 1986·Scottish Medical Journal·B RehmanW P Small
Nov 1, 1987·International Journal of Colorectal Disease·J Windeler, J Köbberling
Aug 19, 1985·The Medical Journal of Australia·C McDonaldK Goulston

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