Abstract
Devices to safely transfer fixed amounts of finger prick blood to rapid diagnostic tests (RDTs) pose a significant challenge, especially in non-laboratory settings. Following the success of an "inverted cup device" for transfer of 5 μL blood, a prototype with a conical cup shape was developed for transfer of 20 μL blood, the amount needed for human immunodeficiency virus or human African trypanosomiasis (HAT) RDTs. This study determined the volume of blood transferred by this new blood transfer device (BTD) and compared its ease of use, safety, and acceptability with that of a plastic pipette when used by health workers (HWs) for HAT RDTs in northwestern Uganda. After a half-day training, 48 HWs had used the two BTDs with at least 10 patients. The conical cup BTD effectively transferred a mean of 22.76 μL of blood (standard deviation 3.31 μL). A significantly higher proportion of HWs were able to collect the full amount of blood using the conical cup BTD, as compared with the pipette (92.4% versus 74.2%, P < 0.001). In HW questionnaires, the conical cup BTD scored higher than the pipette in various aspects of ease of use and safety. In addition, HWs preferred the conical cup BTD (79%), indicating that it was easy to handle, mad...Continue Reading
References
Mar 5, 2004·Tropical Medicine & International Health : TM & IH·Mayfong MayxayNicholas J White
Oct 20, 2006·Transactions of the Royal Society of Tropical Medicine and Hygiene·Waverly RennieSteven Harvey
Nov 16, 2007·Malaria Journal·Jennifer LuchavezDavid Bell
Nov 23, 2007·Transactions of the Royal Society of Tropical Medicine and Hygiene·Carole FoggJean-Paul Guthmann
Feb 27, 2008·Tropical Medicine & International Health : TM & IH·Osama M E SeidahmedEldirdieri S Ahmed
Jul 16, 2008·Malaria Journal·Anna H RoukensLeo G Visser
Aug 23, 2008·Malaria Journal·Steven A HarveyDavid R Bell
Feb 7, 2009·PloS One·Derryck B KlarkowskiDaniel P O'Brien
Feb 10, 2011·Malaria Journal·Heidi HopkinsDavid Bell
Jan 13, 2012·PloS One·Michelle S HsiangBryan Greenhouse
Jul 6, 2012·The American Journal of Tropical Medicine and Hygiene·Helen CounihanDavid Bell
Feb 27, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J MalthaJ Jacobs
Sep 21, 2013·Journal of Medical Microbiology·Joel C Mouatcho, J P Dean Goldring
Jun 14, 2014·Malaria Journal·Esmée RuizendaalPetra F Mens
Dec 19, 2014·PLoS Neglected Tropical Diseases·Jeremy M SternbergJoseph M Ndung'u
May 20, 2017·BMC Public Health·Matthew R Boyce, Wendy P O'Meara
Jul 4, 2017·PloS One·Crispin LumbalaJoseph M Ndung'u