PMID: 2503192Jul 1, 1989Paper

Accuracy in clinically evaluating pigmented lesions

BMJ : British Medical Journal
R K CurleyR A Marsden

Abstract

To determine the ability of three doctors experienced in managing melanocytic lesions to diagnose correctly melanoma, dysplastic naevi, and various benign pigmented lesions. Independent clinical evaluation and histopathological assessment. Pigmented lesion clinic, which patients attend without an appointment for early diagnosis of melanoma. 86 Patients with lesions that were judged to be benign by at least one of the three doctors. The lesions were excised under local anaesthesia and sent for histopathological examination in coded bottles without clinical details. Comparison of clinical with histopathological diagnosis for each lesion. A total of 120 lesions were evaluated by at least two of the three doctors. The histopathological diagnoses were made by the same pathologist. The overall sensitivity (diagnostic accuracy) for the three doctors for all types of lesion was 50%. Of the 39 dysplastic naevi, only 19 were identified correctly by all observers, and a further 24 banal lesions were wrongly diagnosed as dysplastic by at least one doctor. Particular difficulty was experienced with small (less than 5 mm), flat lesions, which can be banal or potentially malignant. Critical diagnosis and management decisions concerning pigmen...Continue Reading

References

Oct 1, 1975·Archives of Dermatology·A W KopfR S Bart
Jun 14, 1986·British Medical Journal·A J SwerdlowD J Hole
Mar 21, 1987·British Medical Journal·F H Rampen, B A Fleuren
Jan 17, 1987·British Medical Journal·J S EnglishD J Hole
May 1, 1988·The British Journal of Dermatology·J S EnglishD J Hole
Jun 1, 1988·The British Journal of Dermatology·J J GrobJ J Bonerandi
Dec 1, 1986·Journal of the American Academy of Dermatology·F H RampenJ B Boezeman
Sep 1, 1987·Journal of the American Academy of Dermatology·E A HollyS H Chiu
Apr 1, 1986·Journal of the American Academy of Dermatology·B R CassilethW P Walsh
Jan 10, 1985·The New England Journal of Medicine·M H GreeneM C Fraser
Mar 15, 1985·International Journal of Cancer. Journal International Du Cancer·A GreenV Siskind
May 1, 1985·The Journal of Dermatologic Surgery and Oncology·R F WagnerD J Grande
Jun 1, 1985·Histopathology·M G Cook, I Robertson
Oct 1, 1981·Archives of Dermatology·D L Ramsay, A B Fox
Nov 1, 1952·American Journal of Clinical Pathology·M SWERDLOW
Jan 1, 1954·A.M.A. Archives of Dermatology and Syphilology·S W BECKER
Dec 1, 1956·A.M.A. Archives of Dermatology·L F HUBENER, F H MCMULLAN
Apr 1, 1951·The British Journal of Surgery·M R EWING, T POWELL
Jul 1, 1949·Archives of Dermatology and Syphilology·S W BECKER

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Citations

Aug 22, 2007·Archives of Dermatology·Karyn B StitzenbergRobert C Millikan
Mar 25, 2000·Clinical and Experimental Dermatology·A J BedlowC C Harland
Jun 25, 2009·Academic Medicine : Journal of the Association of American Medical Colleges·Richard G B LangleyLinda M Mosher
Feb 25, 1995·BMJ : British Medical Journal·C B Del Mar, A C Green
Jan 21, 2015·International Journal of Dermatology·Pradeep BalasubramanianNidhi Singh
Feb 13, 2014·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·D SgourosG Argenziano
Feb 3, 2009·The British Journal of Dermatology·A GergerJ Smolle
Apr 16, 2002·The British Journal of Dermatology·M MoncrieffP Hall
Sep 1, 1992·Clinical and Experimental Dermatology·F H RampenL A Kiemeney
Jan 1, 1994·The British Journal of Dermatology·M M Bosch, M E Boon
Nov 1, 1995·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·B J ConnemannH H Wolff
Oct 4, 2007·Dermatology : International Journal for Clinical and Investigative Dermatology·Richard G B LangleyChristopher Gallant
Jun 10, 2005·ANZ Journal of Surgery·Edmund W EkTam Dieu
Jul 1, 1997·The Journal of Pathology·M G Cook
Jan 1, 1990·Histopathology·M G Cook, M E Fallowfield
Aug 5, 1989·BMJ : British Medical Journal·P Dobson
Apr 1, 1991·International Journal of Dermatology·H C WilliamsA du Vivier
Mar 26, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Marco BurroniPietro Rubegni

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