Accuracy of cardiac CT, radionucleotide and invasive ventriculography, two- and three-dimensional echocardiography, and SPECT for left and right ventricular ejection fraction compared with cardiac MRI: a meta-analysis

European Heart Journal Cardiovascular Imaging
Christopher A PickettEdward A Hulten

Abstract

Left ventricular ejection fraction (LVEF) and right ventricular ejection fraction (RVEF) are important tools in clinical decision-making. We hypothesized that two-dimensional echocardiography (2DE), three-dimensional echocardiography (3DE), radionucleotide ventriculography (RNV), cardiac computed tomography (CT), gated single-photon emission CT (SPECT), and invasive cardiac cine ventriculography (ICV) provide variable accuracy for LVEF and RVEF when using cardiac magnetic resonance imaging (MRI) as a gold standard. We systematically searched published databases for studies comparing LVEF and RVEF measured by CT, 3DE, 2DE, RNV, ICV, and SPECT compared with MRI. We utilized meta-analytic methods to determine the pooled bias (mean weighted difference), limits of agreement (LOA), and correlation coefficient for each modality. For LVEF, 174 studies (7047 patients) were included. For RVEF, 46 studies (1720 patients) were included. Pooled LOA for LVEF were different between modalities: CT and 3DE had smaller LOA than 2DE, SPECT, ICV, and RNV. 2DE showed the largest LOA and a weaker correlation for LVEF (-13.3 to 12.1%, r = 0.660). For RVEF, CT and 3DE have the best data to support their use with a bias <5% and tight LOA and correlatio...Continue Reading

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Citations

Dec 20, 2015·The American Journal of Cardiology·Stephen WasemillerHelme Silvet
Apr 9, 2016·International Journal of Cardiology·Elena SurkovaLuigi P Badano
Aug 21, 2016·Critical Care : the Official Journal of the Critical Care Forum·Anthony S McLean
Jun 21, 2017·The International Journal of Cardiovascular Imaging·Allard T van den HovenJolien W Roos-Hesselink
Jan 13, 2016·World Journal of Gastroenterology : WJG·Francisco Sampaio, Joana Pimenta
Nov 2, 2019·Hospital Practice·Tanya DuttaWilbert S Aronow
Jul 6, 2020·Heart·Luigi P BadanoDenisa Muraru
Mar 21, 2020·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jin Young KimByoung Wook Choi
Jan 7, 2021·Heart Failure Reviews·Diana GonciarLucia Agoston-Coldea
Oct 8, 2019·Cardiology Clinics·Yu Kang, Marielle Scherrer-Crosbie
Feb 11, 2021·Journal of Cardiovascular Computed Tomography·Edoardo ConteDaniele Andreini
Mar 28, 2021·The International Journal of Cardiovascular Imaging·Claudio Tinoco Mesquita
May 11, 2021·Radiology. Cardiothoracic Imaging·Cynthia PhilipEdward A Hulten
Nov 7, 2020·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Hidehiro NamisakiMasaaki Takeuchi
Dec 21, 2021·European Heart Journal Cardiovascular Imaging·Elena SurkovaWei Li

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