Abstract
The cytological pattern of bacterial vaginosis (BV) in the Papanicolaou smear has a controversial history (coccoid vs. Gardnerella type) that has not allowed an efficient use of cervical/vaginal cytology in the diagnosis of this condition. Our study is an attempt to clarify this topic. To evaluate the accuracy of cervical/vaginal cytology in the diagnosis of BV. 1,896 separate examinations were performed on 1,471 women attending our sexually transmitted diseases center between 1990 and 1993. Amsel's composite clinical criteria were used as a gold standard. The Pap smear was prepared on two slides with the addition of a vaginal specimen. In the 166 cases of BV, sensitivity is 88.7%, and specificity is 98.8%. Positive predictive value is 89.8, and negative predictive value is 98.7. Kendall's correlation coefficient is 0.88 (p < 0.001). Our findings support the validity of the vaginal Pap smear in diagnosing BV and suggest the screening of such a disease.
References
Jun 29, 1978·The New England Journal of Medicine·T A PheiferK K Holmes
May 1, 1979·The Journal of Clinical Investigation·K C ChenK K Holmes
Oct 1, 1991·American Journal of Obstetrics and Gynecology·P A Mårdh
Aug 18, 1989·JAMA : the Journal of the American Medical Association
Jan 1, 1989·American Journal of Obstetrics and Gynecology·J J Platz-ChristensenL Bondeson
Apr 1, 1988·American Journal of Obstetrics and Gynecology·D A EschenbachK K Holmes
Sep 1, 1987·Diagnostic Cytopathology·G GiacominiA D'Acunto
Feb 25, 1967·Nature·D M Jones, J Davson
Jul 1, 1983·Journal of Clinical Microbiology·C A SpiegelK K Holmes
Jan 1, 1983·British Journal of Hospital Medicine·S G Dawson, J R Harris
Dec 28, 1995·The New England Journal of Medicine·J C HauthR L Copper
Dec 28, 1995·The New England Journal of Medicine·S L HillierA V Rao
Aug 1, 1993·American Journal of Obstetrics and Gynecology·D A Eschenbach
Oct 1, 1996·Obstetrics and Gynecology·J R SchwebkeR L Sweet
Citations
Nov 30, 2000·Current Infectious Disease Reports·D E Soper
May 1, 2007·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·A KaraniM Temmerman
Apr 17, 2007·Best Practice & Research. Clinical Obstetrics & Gynaecology·Gilbert G G Donders
Feb 18, 2003·Cancer·Mathilde E BoonLambrecht P Kok
Aug 24, 2002·American Journal of Obstetrics and Gynecology·Mathilde E BoonLambrecht P Kok
Feb 26, 2011·American Journal of Clinical Pathology·Angelique W LeviDavid C Chhieng
Apr 16, 2015·MBio·Sujatha SrinivasanDavid N Fredricks
Jul 7, 2007·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·K ErikssonP G Larsson
Dec 29, 2007·Journal of Lower Genital Tract Disease·Valerie A Fitzhugh, Debra S Heller
Mar 18, 2006·Diagnostic Cytopathology·Michelle G DiscacciatiEliana B L Montemor
Nov 8, 2002·Acta Obstetricia Et Gynecologica Scandinavica·Bo JacobssonJens Jörgen Platz-Christensen
Sep 26, 2000·Diagnostic Cytopathology·G Giacomini