Accuracy of computed tomographic features in differentiating intestinal tuberculosis from Crohn's disease: a systematic review with meta-analysis

Intestinal research
Saurabh KediaVineet Ahuja

Abstract

Abdominal computed tomography (CT) can noninvasively image the entire gastrointestinal tract and assess extraintestinal features that are important in differentiating Crohn's disease (CD) and intestinal tuberculosis (ITB). The present meta-analysis pooled the results of all studies on the role of CT abdomen in differentiating between CD and ITB. We searched PubMed and Embase for all publications in English that analyzed the features differentiating between CD and ITB on abdominal CT. The features included comb sign, necrotic lymph nodes, asymmetric bowel wall thickening, skip lesions, fibrofatty proliferation, mural stratification, ileocaecal area, long segment, and left colonic involvements. Sensitivity, specificity, positive and negative likelihood ratios, and diagnostic odds ratio (DOR) were calculated for all the features. Symmetric receiver operating characteristic curve was plotted for features present in >3 studies. Heterogeneity and publication bias was assessed and sensitivity analysis was performed by excluding studies that compared features on conventional abdominal CT instead of CT enterography (CTE). We included 6 studies (4 CTE, 1 conventional abdominal CT, and 1 CTE+conventional abdominal CT) involving 417 and 19...Continue Reading

References

Dec 1, 1995·Clinical and Experimental Immunology·R DuchmannK H Meyer zum Büschenfelde
Jul 1, 1996·Acta Radiologica·C LundstedtI Kagevi
Nov 1, 1995·Diagnostic Microbiology and Infectious Disease·H D FriedmanM T Cynamon
Mar 1, 1997·Radiology·J S WillsF J Denstman
Aug 26, 1998·European Journal of Radiology·D Makanjuola
Jun 26, 1999·Gastroenterology·P DesreumauxJ F Colombel
Jun 7, 2002·International Journal of Colorectal Disease·Frank SchmitzUlrich R Fölsch
Oct 16, 2004·Journal of Gastroenterology and Hepatology·Nikhil PatelParijat Gupte
Feb 3, 2006·International Journal of Clinical Practice·Z Y Zhou, H S Luo
Jul 29, 2006·Journal of Clinical Pathology·R KirschP W Friederich
Nov 7, 2007·Gastroenterology·Susanna Nikolaus, Stefan Schreiber
Jan 22, 2008·World Journal of Gastroenterology : WJG·Deepak N AmarapurkarPriyamvada S Rane
May 16, 2008·American Journal of Clinical Pathology·Anna B PulimoodHelen D Donoghue
Sep 5, 2008·Digestive Diseases and Sciences·Kshaunish DasGovind K Makharia
Jan 21, 2010·The American Journal of Gastroenterology·Govind K MakhariaSiddhartha Datta Gupta
Dec 3, 2010·Journal of Crohn's & Colitis·Gert Van AsscheUNKNOWN European Crohn's and Colitis Organisation (ECCO)
Jan 29, 2011·World Journal of Gastroenterology : WJG·Anna Benjamin PulimoodBalakrishna Siddhartha Ramakrishna
Nov 15, 2012·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Vineet Ahuja, Rakesh K Tandon
Sep 21, 2013·Journal of Computer Assisted Tomography·Yoon Hea ParkSung Pil Hong
Dec 18, 2014·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·H AdadaT Roy
Feb 11, 2015·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Bikramjit SinghVineet Ahuja
May 15, 2015·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Saurabh KediaVineet Ahuja

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Citations

Sep 29, 2019·Expert Review of Gastroenterology & Hepatology·Pradeep GoyalVishal Sharma
Jan 8, 2018·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Saurabh KediaUNKNOWN for Indian Society of Gastroenterology Task Force on Inflammatory Bowel Disease
Oct 26, 2018·World Journal of Emergency Surgery : WJES·Fikri M Abu-Zidan, Arif Alper Cevik
Aug 25, 2018·Gastroenterology Research and Practice·Jingyun ChengGuangyao Wu
Feb 1, 2019·World Journal of Gastroenterology : WJG·Saurabh KediaVineet Ahuja
Apr 23, 2020·Journal of Family Medicine and Primary Care·Nehal AggarwalAtul Goel
Apr 24, 2018·Case Reports in Gastrointestinal Medicine·Raja Chandra ChakinalaBrad Dworkin
Feb 9, 2021·JGH Open : an Open Access Journal of Gastroenterology and Hepatology·Saurabh Kedia, Vineet Ahuja
Mar 9, 2021·Curēus·Hansang ParkJungrak Hong

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Methods Mentioned

BETA
biopsies
biopsy

Software Mentioned

Metadisc
Stata
QUADAS

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