Accuracy of intraoperative frozen section in the diagnosis of ovarian neoplasms: experience at a tertiary oncology center

World Journal of Surgical Oncology
Amita MaheshwariHemant B Tongaonkar

Abstract

Epithelial ovarian neoplasms are an important cause of morbidity and mortality in women. The surgical management of ovarian neoplasms depends on their correct categorization as benign, borderline or malignant. This study was undertaken to evaluate the accuracy of intra-operative frozen section in the diagnosis of various categories of ovarian neoplasms. Intraoperative frozen section diagnosis was retrospectively evaluated in 217 patients with suspected ovarian neoplasms who underwent surgery as primary line of therapy at our institution. This was compared with the final histopathologic diagnosis on paraffin sections. In 7 patients (3.2%) no opinion on frozen section was possible. In the remaining 210 patients frozen section report had a sensitivity of 100%, 93.5% and 45.5% for benign, malignant and borderline tumors. The corresponding specificities were 93.2%, 98.3% and 98.5% respectively. The overall accuracy of frozen section diagnosis was 91.2%. The majority of cases of disagreement were in the mucinous and borderline tumors. Intraoperative frozen section has high accuracy in the diagnosis of suspected ovarian neoplasms. It is a valuable tool to guide the surgical management of these patients and should be routinely used in ...Continue Reading

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Citations

Sep 19, 2009·The Journal of International Medical Research·B GorisekI Krajnc
Mar 2, 2016·The Cochrane Database of Systematic Reviews·Nithya D G RatnaveluRaj Naik
Feb 10, 2012·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Mark K Heatley
Nov 22, 2012·The Journal of Obstetrics and Gynaecology Research·Renuka Malipatil, Julian A Crasta
Jun 7, 2019·Indian Journal of Surgical Oncology·Nyengidiki T KennedyAbraham Peedicayil
Sep 8, 2011·BJOG : an International Journal of Obstetrics and Gynaecology·P A CrossA D Lopes

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