Accuracy of routine treatment planning 4-dimensional and deep-inspiration breath-hold computed tomography delineation of the left anterior descending artery in radiation therapy

International Journal of Radiation Oncology, Biology, Physics
Benjamin WhiteStefan Both

Abstract

To assess the feasibility of radiation therapy treatment planning 4-dimensional computed tomography (4DCT) and deep-inspiration breath-hold (DIBH) CT to accurately contour the left anterior descending artery (LAD), a primary indicator of radiation-induced cardiac toxicity for patients undergoing radiation therapy. Ten subjects were prospectively imaged with a cardiac-gated MRI protocol to determine cardiac motion effects, including the displacement of a region of interest comprising the LAD. A series of planar views were obtained and resampled to create a 3-dimensional (3D) volume. A 3D optical flow deformable image registration algorithm determined tissue displacement during the cardiac cycle. The measured motion was then used as a spatial boundary to characterize motion blurring of the radiologist-delineated LAD structure for a cohort of 10 consecutive patients enrolled prospectively on a breast study including 4DCT and DIBH scans. Coronary motion-induced blurring artifacts were quantified by applying an unsharp filter to accentuate the LAD structure despite the presence of motion blurring. The 4DCT maximum inhalation and exhalation respiratory phases were coregistered to determine the LAD displacement during tidal respiratio...Continue Reading

References

Nov 25, 2000·Journal of Biomechanical Engineering·Z Ding, M H Friedman
Apr 1, 1959·Circulation·F L RODRIGUEZ, S L ROBBINS
Sep 2, 2004·IEEE Transactions on Medical Imaging·Guy ShechterElliot R McVeigh
Mar 10, 2006·IEEE Transactions on Medical Imaging·Guy ShechterElliot R McVeigh
Dec 26, 2006·International Journal of Radiation Oncology, Biology, Physics·Susanne Schultz-Hector, Klaus-Rüdiger Trott
Feb 6, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Lawrence F PaszatAndreas Wielgosz
Apr 24, 2007·International Journal of Radiation Oncology, Biology, Physics·Reshma JagsiLori J Pierce
May 22, 2007·Lancet·Matthias BramkampNils Kucher
Jun 6, 2007·Radiation Oncology·Carsten NiederMichael Molls
Jul 4, 2007·International Journal of Radiation Oncology, Biology, Physics·Jacques H BorgerFlora E van Leeuwen
Jul 20, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Candace R CorreaEleanor E Harris
Jan 15, 2008·International Journal of Radiation Oncology, Biology, Physics·Xiong WeiZhongxing Liao
Mar 7, 2009·Physics in Medicine and Biology·Richard CastilloThomas Guerrero
Mar 5, 2010·International Journal of Radiation Oncology, Biology, Physics·Giovanna GagliardiLawrence B Marks
May 18, 2010·International Journal of Radiation Oncology, Biology, Physics·Rajko TopolnjakCorine van Vliet-Vroegindeweij
Jun 29, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·D BovelliUNKNOWN ESMO Guidelines Working Group
Sep 18, 2010·Circulation. Cardiovascular Imaging·Daniel B EnnisRalph A H Stewart
Nov 13, 2010·Thoracic Surgery Clinics·Nicolas Girard, Françoise Mornex
Dec 17, 2010·The British Journal of Radiology·M C AznarL Specht
Mar 30, 2011·International Journal of Radiation Oncology, Biology, Physics·Xiaochun WangT Kuan Yu
Dec 20, 2011·Seminars in Radiation Oncology·Philip PoortmansHarry Bartelink
Mar 15, 2013·The New England Journal of Medicine·Sarah C DarbyPer Hall

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Citations

Jan 15, 2017·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Jie LeeYu-Jen Chen
Nov 23, 2017·The British Journal of Radiology·David H ThomasDaniel Low
Aug 31, 2018·Cardiology Research and Practice·Azira KhalilKhin Wee Lai
Aug 31, 2020·International Journal of Radiation Oncology, Biology, Physics·Eliot NicolasYoulia Kirova
Oct 3, 2020·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Pierre LoapYoulia Kirova

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