Accuracy of the Radiographic Assessment of Lung Edema Score for the Diagnosis of ARDS.

Frontiers in Physiology
Claudio ZimatoreMarcus J Schultz

Abstract

Background: Bilateral opacities on chest radiographs are part of the Berlin Definition for Acute Respiratory Distress Syndrome (ARDS) but have poor interobserver reliability. The "Radiographic Assessment of Lung Edema" (RALE) score was recently proposed for evaluation of the extent and density of alveolar opacities on chest radiographs of ARDS patients. The current study determined the accuracy of the RALE score for the diagnosis and the prognosis of ARDS. Methods:Post-hoc analysis of a cohort of invasively ventilated intensive care unit (ICU) patients expected to need invasive ventilation for >24 h. The Berlin Definition was used as the gold standard. The RALE score was calculated for the first available chest radiograph after start of ventilation in the ICU. The primary endpoint was the diagnostic accuracy for ARDS of the RALE score. Secondary endpoints included the prognostic value of the RALE score for ICU and hospital mortality, and the association with ARDS severity, and the PaO2/FiO2. Receiver operating characteristic (ROC) curves were constructed, and the optimal cutoff was used to determine sensitivity, specificity and the negative and positive predictive value of the RALE score for ARDS. Results: The study included 13...Continue Reading

References

Mar 24, 2004·Journal of Intensive Care Medicine·Beatrice Trotman-Dickenson
Jan 1, 1950·Cancer·W J YOUDEN
Aug 3, 2005·Journal of Intensive Care Medicine·Marleen E GraatMarcus J Schultz
Jul 20, 2006·BMC Medical Imaging·Marleen E GraatMarcus J Schultz
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Jan 26, 2018·Intensive Care Medicine·Veronica VercesiUNKNOWN Lung Ultrasound Consortium
Jul 14, 2020·Chest·Matthieu JabaudonUNKNOWN LIVE Study Group and the AZUREA Network

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