Accuracy of the umbilical arteries Doppler flow velocity waveforms in detecting adverse perinatal outcomes in a high-risk population

Acta Obstetricia Et Gynecologica Scandinavica
T TodrosG Pilu

Abstract

To define the accuracy of the umbilical artery Doppler flow velocity waveforms, according to different cut-off values, in predicting adverse perinatal outcomes among fetuses at high risk of hypoxic complications. Two hundred and sixty-five pregnant women with diagnosis of small for gestational age fetus and/or pregnancy induced hypertension studied in four Italian ultrasound units. Prospective study. Serial Doppler ultrasound measurements of the umbilical artery were performed. Results were not available for clinical management. Cut-off curves, corresponding to different age-specific centiles of the pulsatility index distribution among pregnancies resulting in healthy newborns, regardless of birthweight, were computed by regression methods. Sensitivity, specificity, positive predictive value and negative predictive value of such cut-off curves, and of absent/reverse end-diastolic flow, in predicting different adverse outcomes were estimated. The adverse outcomes were: perinatal or neonatal death (OUTCOME 1). Death or Apgar<7 at 5' or need for admission to intensive care unit or other hypoxic related abnormalities (OUTCOME 2). Either OUTCOME 2 or birthweight<l0th centile (OUTCOME 3). Both OUTCOME 2 and birthweight<10th centile (...Continue Reading

Citations

May 17, 2005·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Tullia TodrosLuana Paulesu
Nov 13, 2013·Journal de gynécologie, obstétrique et biologie de la reproduction·M-V Senat, V Tsatsaris
Jan 15, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Giorgina B PiccoliTullia Todros
Jan 5, 2012·World Journal of Gastroenterology : WJG·Simona CardaropoliTullia Todros
Jun 9, 2012·Journal of Perinatology : Official Journal of the California Perinatal Association·N C NguyenJ L Daniels
Dec 17, 2008·The Journal of Physiology·Lucrecia PostigoStacy Zamudio
Jan 15, 2011·Placenta·T TodrosI Caniggia
Apr 9, 2008·Journal of Affective Disorders·Giuseppe MainaTullia Todros
Sep 18, 2007·Ultrasound in Medicine & Biology·Sonia BalbisCaterina Guiot
Feb 7, 2008·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C GuiotT Todros
May 1, 2012·Prenatal Diagnosis·Elena OlearoTullia Todros
Jun 9, 2004·Best Practice & Research. Clinical Obstetrics & Gynaecology·Clare Gribbin, David James
Mar 23, 2015·Journal of Reproductive Immunology·Simona CardaropoliTullia Todros
Apr 9, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J BrodszkiK Marsál
Jun 6, 2002·Acta Obstetricia Et Gynecologica Scandinavica·Edoardo Di NaroVincenzo D' Addario
Nov 15, 2018·Journal of Cellular Physiology·Giovanni TossettaDaniela Marzioni
Dec 23, 2003·BJOG : an International Journal of Obstetrics and Gynaecology·T TodrosC De Felice
Nov 19, 2020·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M KinoshitaK Maršál

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